PDB entry 2uwy

View 2uwy on RCSB PDB site
Description: active site restructuring regulates ligand recognition in class a penicillin-binding proteins
Deposited on 2007-03-23, released 2007-04-24
The last revision was dated 2010-05-26, with a file datestamp of 2010-05-21.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.17
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: penicillin-binding protein 1b
    Species: Streptococcus pneumoniae [TaxId:171101]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7CRA4
      • engineered mutation (388-389)
  • Chain 'B':
    Compound: penicillin-binding protein 1b
    Species: Streptococcus pneumoniae [TaxId:171101]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7CRA4
      • engineered mutation (388-389)
  • Heterogens: CEF, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2uwyA (A:)
dissiseitysdgtviasiesdllrqdflpsgtvtgisqdylyfttlaeaqermydylaq
rdnvsakelkneatqkfyrdlaakeienggykitttidqkihsamqsavadygyllddgt
grvevgnvlmdnqtgailgfvggrnyqenqnnhafdtkrspasttkpllaygiaidqglm
gsetilsnyptnfangnpimyanskgtgmmtlgealnyswnipaywtyrmlrengvdvkg
ymekmgyeipeygieslpmgggievtvaqhtngyqtlanngvyhqkhviskieaadgrvv
yeyqdkpvqvyskatatimqgllrevlssrvtttfksnltslnptlanadwigktgttnq
denmwlmlstprltlggwighddnhslsqqagysnnsnymahlvnaiqqaspsiwgnerf
aldpsvvksevlkstgqkpgkvsvegkevevtgstvtsywanksgapatsyrfaiggsda
dyqnawssivgslp

    Sequence, based on observed residues (ATOM records):
    >2uwyA (A:)
siseitysdgtviasidylyfttlaeaqermydylaqrdnvsakelkneatqkfyrdlaa
keienggykitttidqkihsamqsavadygyllddgtgrvevgnvlmdnqtgailgfvgg
rnyqenqnnhafdtkrspasttkpllaygiaidqglmgsetilsnyptnfangnpimyan
skgtgmmtlgealnyswnipaywtyrmlrengvdvkgymekmgyeipeygieslpmgggi
evtvaqhtngyqtlanngvyhqkhviskieaadgrvvyeyqdkpvqvyskatatimqgll
revlssrvtttfksnltslnptlanadwigktgttnqdenmwlmlstprltlggwighdd
nhslsqqagysnnsnymahlvnaiqqaspsiwgnerfaldpsvvksevlkstgqkpgkvs
vegkevevtgstvtsywanksgapatsyrfaiggsdadyqnawssivgs

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2uwyB (B:)
dissiseitysdgtviasiesdllrqdflpsgtvtgisqdylyfttlaeaqermydylaq
rdnvsakelkneatqkfyrdlaakeienggykitttidqkihsamqsavadygyllddgt
grvevgnvlmdnqtgailgfvggrnyqenqnnhafdtkrspasttkpllaygiaidqglm
gsetilsnyptnfangnpimyanskgtgmmtlgealnyswnipaywtyrmlrengvdvkg
ymekmgyeipeygieslpmgggievtvaqhtngyqtlanngvyhqkhviskieaadgrvv
yeyqdkpvqvyskatatimqgllrevlssrvtttfksnltslnptlanadwigktgttnq
denmwlmlstprltlggwighddnhslsqqagysnnsnymahlvnaiqqaspsiwgnerf
aldpsvvksevlkstgqkpgkvsvegkevevtgstvtsywanksgapatsyrfaiggsda
dyqnawssivgslp

    Sequence, based on observed residues (ATOM records):
    >2uwyB (B:)
seitysdgtviasiedylyfttlaeaqermydylaqrdneatqkfyrdlaaggykittti
dqkihsamqsavadygyllddgtgrvevgnvlmdnqtgailgfvggrnyqenqnnhafdt
krspasttkpllaygiaidqglmgsetilsnyptnfangnpimyanskgtgmmtlgealn
yswnipaywtyrmlrengvdvkgymekmgyeipeygieslpmgggievtvaqhtngyqtl
anngvyhqkhviskieaadgrvvyeyqdkpvqvyskatatimqgllrevlssrvtttfks
nltslnptlanadwigktgttnqdenmwlmlstprltlggwighddnhslsqqagysnns
nymahlvnaiqqaspsiwgnerfaldpsvvksevlkstgqkpgkvsvegkevevtgstvt
sywanksgapatsyrfaiggsdadyqnawssivgs