PDB entry 2uwp

View 2uwp on RCSB PDB site
Description: factor xa inhibitor complex
Class: hydrolase
Keywords: target hopping, serine protease, egf-like domain, polymorphism, glycoprotein, hydroxylation, calcium, zymogen, complex, protease, hydrolase, blood coagulation, gamma- carboxyglutamic acid, cleavage on pair of basic residues
Deposited on 2007-03-22, released 2007-05-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.186
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: coagulation factor x
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2uwpa_
  • Chain 'B':
    Compound: coagulation factor x
    Species: Homo sapiens [TaxId:9606]
    Domains in SCOPe 2.08: d2uwpb_
  • Heterogens: 894, CA, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2uwpA (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
kshapevitssplk

    Sequence, based on observed residues (ATOM records): (download) 
    >2uwpA (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2uwpB (B:)
eemkkghlerecmeetcsyeearevfedsdktnefwnkykdgdqcetspcqnqgkckdgl
geytctclegfegkncelftrklcsldngdcdqfcheeqnsvvcscargytladngkaci
ptgpypcgkqtler

    Sequence, based on observed residues (ATOM records): (download) 
    >2uwpB (B:)
rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtl