PDB entry 2tpi

View 2tpi on RCSB PDB site
Description: on the disordered activation domain in trypsinogen. chemical labelling and low-temperature crystallography
Class: Hydrolase/hydrolase INHIBITOR
Keywords: COMPLEX (PROTEINASE/INHIBITOR), Hydrolase/hydrolase INHIBITOR COMPLEX
Deposited on 1981-10-26, released 1982-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.2
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'I':
    Compound: trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2tpii_
  • Chain 'Z':
    Compound: trypsinogen
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2tpiz_
  • Heterogens: ILE, VAL, HG, HOH

PDB Chain Sequences:

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2tpiI (I:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga

    Sequence, based on observed residues (ATOM records): (download) 
    >2tpiI (I:)
pdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >2tpiZ (Z:)
vddddkivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedn
invvegneqfisasksivhpsynsntlnndimliklksaaslnsrvasislptscasagt
qclisgwgntkssgtsypdvlkclkapilsdsscksaypgqitsnmfcagyleggkdscq
gdsggpvvcsgklqgivswgsgcaqknkpgvytkvcnyvswikqtiasn

    Sequence, based on observed residues (ATOM records): (download) 
    >2tpiZ (Z:)
gytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedninvvegneq
fisasksivhpsynsntlnndimliklksaaslnsrvasislptscasagtqclisgwgn
tkssgtsypdvlkclkapilsdsscksaypgqitsnmfcagyleggkdscqgdsggpvvc
sgklqgivswgsgcaqknkpgvytkvcnyvswikqtiasn