PDB entry 2toh

View 2toh on RCSB PDB site
Description: tyrosine hydroxylase catalytic and tetramerization domains from rat
Class: hydroxylase
Keywords: hydroxylase, neurotransmitter biosynthesis, non-heme iron, pterin co-substrate, catecholamine biosynthesis, oxidoreductase
Deposited on 1998-08-26, released 1999-08-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.207
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tyrosine 3-monooxygenase
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04177 (Start-342)
      • modified residue (144)
    Domains in SCOPe 2.08: d2toha_
  • Heterogens: FE, CL, HBI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2tohA (A:)
vrsaredkvpwfprkvseldkchhlvtkfdpdldldhpgfsdqvyrqrrkliaeiafqyk
hgepiphveytaeeiatwkevyvtlkglyathacrehlegfqllerycgyredsipqled
vsrflkertgfqlrpvagllsardylaslafrvfqctqyirhasspmhspepdcchellg
hvpmladrtfaqfsqdiglaslgasdeeieklstvywftvefglckqngelkaygaglls
sygellhslseepevrafdpdtaavqpyqdqtyqpvyfvsesfndakdklrnyasriqrp
fsvkfdpytlaidvldsphtiqrslegvqdelhtlahalsais

    Sequence, based on observed residues (ATOM records): (download) 
    >2tohA (A:)
redkvpwfprkvseldkchhlvtpdldldhpgfsdqvyrqrrkliaeiafqykhgepiph
veytaeeiatwkevyvtlkglyathacrehlegfqllerycgyredsipqledvsrflke
rtgfqlrpvagllsardylaslafrvfqctqyirhasspmhspepdcchellghvpmlad
rtfaqfsqdiglaslgasdeeieklstvywftvefglckqngelkaygagllssygellh
slseepevrafdpdtaavqpyqdqtyqpvyfvsesfndakdklrnyasriqrpfsvkfdp
ytlaidvldsphtiqrslegvqdelhtlahalsais