PDB entry 2tmk

View 2tmk on RCSB PDB site
Description: yeast thymidylate kinase complexed with 3'-azido-3'-deoxythymidine monophosphate (azt-mp)
Class: phosphotransferase
Keywords: transferase (phosphotransferase), kinase, thymidine activation pathway, enzyme, azt
Deposited on 1997-06-12, released 1998-06-17
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.182
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CDC8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2tmka_
  • Chain 'B':
    Compound: thymidylate kinase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CDC8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2tmkb_
  • Heterogens: SO4, ATM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2tmkA (A:)
mmgrgkliliegldrtgkttqcnilykklqpnckllkfperstrigglineyltddsfql
sdqaihllfsanrweivdkikkdllegknivmdryvysgvaysaakgtngmdldwclqpd
vgllkpdltlflstqdvdnnaeksgfgderyetvkfqekvkqtfmklldkeirkgdesit
ivdvtnkgiqevealiwqivepvlsthidhdkfsff

    Sequence, based on observed residues (ATOM records): (download) 
    >2tmkA (A:)
grgkliliegldrtgkttqcnilykklqpnckllkfperstrigglineyltddsfqlsd
qaihllfsanrweivdkikkdllegknivmdryvysgvaysaakgtngmdldwclqpdvg
llkpdltlflstqfgderyetvkfqekvkqtfmklldkeirkgdesitivdvtnkgiqev
ealiwqivepvlsthidhdkfsff

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2tmkB (B:)
mmgrgkliliegldrtgkttqcnilykklqpnckllkfperstrigglineyltddsfql
sdqaihllfsanrweivdkikkdllegknivmdryvysgvaysaakgtngmdldwclqpd
vgllkpdltlflstqdvdnnaeksgfgderyetvkfqekvkqtfmklldkeirkgdesit
ivdvtnkgiqevealiwqivepvlsthidhdkfsff

    Sequence, based on observed residues (ATOM records): (download) 
    >2tmkB (B:)
grgkliliegldrtgkttqcnilykklqpnckllkfperstrigglineyltddsfqlsd
qaihllfsanrweivdkikkdllegknivmdryvysgvaysaakgtngmdldwclqpdvg
llkpdltlflstqfgderyetvkfqekvkqtfmklldkeirkgdesitivdvtnkgiqev
ealiwqivepvlsthidhdkfsff