PDB entry 2src

View 2src on RCSB PDB site
Description: crystal structure of human tyrosine-protein kinase c-src, in complex with amp-pnp
Class: tyrosine-protein kinase
Keywords: src, tyrosine-protein kinase, phosphorylation, sh2, sh3, phosphotyrosine, proto-oncogene, phosphotransferase
Deposited on 1998-12-29, released 1999-07-22
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.226
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tyrosine-protein kinase src
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12931 (Start-451)
      • modified residue (445)
    Domains in SCOP 1.73: d2srca1, d2srca2, d2srca3
  • Heterogens: ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2srcA (A:)
mvttfvalydyesrtetdlsfkkgerlqivnntegdwwlahslstgqtgyipsnyvapsd
siqaeewyfgkitrreserlllnaenprgtflvresettkgayclsvsdfdnakglnvkh
ykirkldsggfyitsrtqfnslqqlvayyskhadglchrlttvcptskpqtqglakdawe
ipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkklrhek
lvqlyavvseepiyivteymskgslldflkgetgkylrlpqlvdmaaqiasgmayvermn
yvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaalygrfti
ksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrk
epeerptfeylqafledyftstepqyqpgenl

    Sequence, based on observed residues (ATOM records): (download) 
    >2srcA (A:)
ttfvalydyesrtetdlsfkkgerlqivnntegdwwlahslstgqtgyipsnyvapsdsi
qaeewyfgkitrreserlllnaenprgtflvresettkgayclsvsdfdnakglnvkhyk
irkldsggfyitsrtqfnslqqlvayyskhadglchrlttvcptskpqtqglakdaweip
reslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkklrheklv
qlyavvseepiyivteymskgslldflkgetgkylrlpqlvdmaaqiasgmayvermnyv
hrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaalygrftiks
dvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkep
eerptfeylqafledyftstepqyqpgenl