PDB entry 2roc

View 2roc on RCSB PDB site
Description: Solution structure of Mcl-1 Complexed with Puma
Class: Apoptosis
Keywords: Mcl-1, Bcl-2, apoptosis, Puma, BH3-only, Cytoplasm, Developmental protein, Differentiation, Membrane, Mitochondrion, Nucleus, Phosphoprotein, Transmembrane, Ubl conjugation
Deposited on 2008-03-17, released 2008-07-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
  Species: MUS MUSCULUS
  Gene: mcl-1
  Database cross-references and differences (RAF-indexed):
  • Uniprot P97287 (5-161)
    • expression tag (0-4)
  Domains in SCOPe 2.06: d2roca2, d2roca3
• Chain 'B':
  Compound: Bcl-2-binding component 3
  Species: MUS MUSCULUS
  Gene: Puma
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q99ML1 (0-25)
    • engineered (14)
    • expression tag (26)

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2rocA (A:)
  gplgseddlyrqsleiisrylreqatgskdskplgeagaagrraletlrrvgdgvqrnhe
  tafqgmlrkldiknegdvksfsrvmvhvfkdgvtnwgrivtlisfgafvakhlksvnqes
  fieplaetitdvlvrtkrdwlvkqrgwdgfveffhvqdlegg
  

  
  
• Chain 'B':
  No sequence available.