PDB entry 2rl3

View 2rl3 on RCSB PDB site
Description: Crystal structure of the OXA-10 W154H mutant at pH 7
Class: hydrolase
Keywords: OXA-10, carboxylated lysine, class D beta-lactamase, Antibiotic resistance, Hydrolase
Deposited on 2007-10-18, released 2008-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.171
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase PSE-2
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pse2, oxa10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14489 (1-End)
      • initiating methionine (0)
      • engineered (135)
    Domains in SCOPe 2.08: d2rl3a_
  • Chain 'B':
    Compound: Beta-lactamase PSE-2
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pse2, oxa10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14489 (1-247)
      • initiating methionine (0)
      • engineered (135)
    Domains in SCOPe 2.08: d2rl3b_
  • Heterogens: SO4, GOL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2rl3A (A:)
mgsitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfkipnaiigl
etgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkk
fsygnqnisggidkfhlegqlrisavnqvefleslylnklsaskenqlivkealvteaap
eylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkim
esegiigg

    Sequence, based on observed residues (ATOM records): (download) 
    >2rl3A (A:)
mgsitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfkipnaiigl
etgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkk
fsygnqnisggidkfhlegqlrisavnqvefleslylnklsaskenqlivkealvteaap
eylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkim
esegii

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2rl3B (B:)
mgsitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfkipnaiigl
etgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkk
fsygnqnisggidkfhlegqlrisavnqvefleslylnklsaskenqlivkealvteaap
eylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkim
esegiigg