PDB entry 2rkf

View 2rkf on RCSB PDB site
Description: HIV-1 PR resistant mutant + LPV
Class: hydrolase
Keywords: resistence, insertion, HYDROLASE
Deposited on 2007-10-16, released 2008-08-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.194
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: protease retropepsin
  Species: human immunodeficiency virus 1 [TaxId:11676]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot A0F7J4 (0-98)
    • engineered (12)
    • engineered (15)
    • engineered (19)
    • engineered (36)
    • engineered (45)
    • engineered (53)
    • engineered (62)
    • engineered (92)
  Domains in SCOPe 2.08: d2rkfa_
• Chain 'B':
  Compound: protease retropepsin
  Species: human immunodeficiency virus 1 [TaxId:11676]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot A0F7J4 (0-98)
    • engineered (12)
    • engineered (15)
    • engineered (19)
    • engineered (36)
    • engineered (45)
    • engineered (53)
    • engineered (62)
    • engineered (92)
  Domains in SCOPe 2.08: d2rkfb_
• Heterogens: SO4, AB1, GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2rkfA (A:)
  pqitlwqrpfvtvkiagqlmealldtgaddtileemslpgrwtpkvvggiggfmkvrqyd
  qilveicghkvigtvlvgptpaniigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2rkfB (B:)
  pqitlwqrpfvtvkiagqlmealldtgaddtileemslpgrwtpkvvggiggfmkvrqyd
  qilveicghkvigtvlvgptpaniigrnlltqigctlnf