PDB entry 2rii

View 2rii on RCSB PDB site
Description: Crystal Structure of Human Peroxiredoxin I in complex with Sulfiredoxin
Class: oxidoreductase complex
Keywords: protein-protein complex, engineered disulfide bond, sulfinic acid reductase, Antioxidant, Oxidoreductase, Peroxidase, Phosphorylation, Redox-active center, ATP-binding, Magnesium, Nucleotide-binding, ----, OXIDOREDUCTASE COMPLEX
Deposited on 2007-10-11, released 2008-01-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-09-18, with a file datestamp of 2013-09-13.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.242
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxiredoxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PRDX1, PAGA, PAGB, TDPX2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q06830
      • engineered (70)
      • engineered (82)
      • engineered (172)
    Domains in SCOPe 2.08: d2riia_
  • Chain 'B':
    Compound: Peroxiredoxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PRDX1, PAGA, PAGB, TDPX2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q06830
      • engineered (70)
      • engineered (82)
      • engineered (172)
    Domains in SCOPe 2.08: d2riib_
  • Chain 'X':
    Compound: Sulfiredoxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: SRXN1, C20orf139, SRX
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2riix_
  • Chain 'Y':
    Compound: Sulfiredoxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: SRXN1, C20orf139, SRX
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2riiy_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2riiA (A:)
mssgnakighpapnfkatavmpdgqfkdislsdykgkyvvfffypldftfvcpteiiafs
draeefkklnsqvigasvdshfehlawvntpkkqgglgpmniplvsdpkrtiaqdygvlk
adegisfrglfiiddkgilrqitvndlpvgrsvdetlrlvqafqftdkhgevspagwkpg
sdtikpdvqkskeyfskqk

    Sequence, based on observed residues (ATOM records): (download) 
    >2riiA (A:)
sgnakighpapnfkatavmpdgqfkdislsdykgkyvvfffypldftfvcpteiiafsdr
aeefkklnsqvigasvdshfehlawvntpkkqgglgpmniplvsdpkrtiaqdygvlkad
egisfrglfiiddkgilrqitvndlpvgrsvdetlrlvqafqftdkhgevspagwkpgsd
tikp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2riiB (B:)
mssgnakighpapnfkatavmpdgqfkdislsdykgkyvvfffypldftfvcpteiiafs
draeefkklnsqvigasvdshfehlawvntpkkqgglgpmniplvsdpkrtiaqdygvlk
adegisfrglfiiddkgilrqitvndlpvgrsvdetlrlvqafqftdkhgevspagwkpg
sdtikpdvqkskeyfskqk

    Sequence, based on observed residues (ATOM records): (download) 
    >2riiB (B:)
sgnakighpapnfkatavmpdgqfkdislsdykgkyvvfffypldftfvcpteiiafsdr
aeefkklnsqvigasvdshfehlawvntpkkqgglgpmniplvsdpkrtiaqdygvlkad
egisfrglfiiddkgilrqitvndlpvgrsvdetlrlvqafqftdkhgevspagwkpgsd
tikpd

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2riiX (X:)
ghpmsihsgriaavhnvplsvlirplpsvldpakvqslvdtiredpdsvppidvlwikga
qggdyfysfggchryaayqqlqretipaklvqstlsdlrvylgastpdlq

    Sequence, based on observed residues (ATOM records): (download) 
    >2riiX (X:)
sihsgriaavhnvplsvlirplpsvldpakvqslvdtiredpdsvppidvlwikgaqggd
yfysfggchryaayqqlqretipaklvqstlsdlrvylgastpdlq

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >2riiY (Y:)
ghpmsihsgriaavhnvplsvlirplpsvldpakvqslvdtiredpdsvppidvlwikga
qggdyfysfggchryaayqqlqretipaklvqstlsdlrvylgastpdlq

    Sequence, based on observed residues (ATOM records): (download) 
    >2riiY (Y:)
aavhnvplsvlirplpsvldpakvqslvdtiredpdsvppidvlwikgaqggdyfysfgg
chryaayqqlqretipaklvqstlsdlrvylgastpdlq