PDB entry 2rhx

View 2rhx on RCSB PDB site
Description: Crystal structure of the 3-MBT repeats from human L3MBTL1 bound to dimethyl-lysine
Class: transcription
Keywords: Beta Barrel, dimethyl-lysine, Alternative splicing, Chromatin regulator, DNA-binding, Metal-binding, Nucleus, Repressor, Transcription, Transcription regulation, Zinc, Zinc-finger
Deposited on 2007-10-09, released 2007-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.196
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lethal(3)malignant brain tumor-like protein
    Species: Homo sapiens [TaxId:9606]
    Gene: L3MBTL, KIAA0681, L3MBT
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y468 (Start-334)
      • expression tag (335-336)
    Domains in SCOPe 2.08: d2rhxa1, d2rhxa2, d2rhxa3, d2rhxa4
  • Heterogens: SO4, MLY, PG4, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2rhxA (A:)
    gspnspatgekkecwswesyleeqkaitapvslfqdsqavthnkngfklgmklegidpqh
    psmyfiltvaevcgyrlrlhfdgysechdfwvnanspdihpagwfektghklqppkgyke
    eefswsqylrstraqaapkhlfvsqshsppplgfqvgmkleavdrmnpslvcvasvtdvv
    dsrflvhfdnwddtydywcdpsspyihpvgwcqkqgkpltppqdypdpdnfcwekyleet
    gasavptwafkvrpphsflvnmkleavdrrnpalirvasvedvedhrikihfdgwshgyd
    fwidadhpdihpagwcsktghplqpplgprepssavdssgrivtd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2rhxA (A:)
    ecwswesyleeqkaitapvslfqdsqavthnkngfklgmklegidpqhpsmyfiltvaev
    cgyrlrlhfdgysechdfwvnanspdihpagwfektghklqppkgykeeefswsqylrst
    raqaapkhlfvsqshsppplgfqvgmkleavdrmnpslvcvasvtdvvdsrflvhfdnwd
    dtydywcdpsspyihpvgwcqkqgkpltppqdypdpdnfcwekyleetgasavptwafkv
    rpphsflvnmkleavdrrnpalirvasvedvedhrikihfdgwshgydfwidadhpdihp
    agwcsktghplqpplgprepssavd