PDB entry 2rhg

View 2rhg on RCSB PDB site
Description: Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine
Class: lyase
Keywords: AROMATIC AMINO ACID BIOSYNTHESIS, TRYPTOPHAN BIOSYNTHESIS, CARBON-OXYGEN LYASE, AMINOACID BIOSYNTHESIS, LYASE, ALLOSTERIC ENZYME, PYRIDOXAL PHOSPHATE, Amino-acid biosynthesis
Deposited on 2007-10-09, released 2007-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.212
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tryptophan synthase alpha chain
    Species: Salmonella typhimurium [TaxId:602]
    Gene: trpA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2rhga_
  • Chain 'B':
    Compound: tryptophan synthase beta chain
    Species: Salmonella typhimurium [TaxId:602]
    Gene: TrpB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2rhgb_
  • Heterogens: NA, IGP, PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2rhgA (A:)
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvtgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivki
ieknlaspkqmlaelrsfvsamkaasra

    Sequence, based on observed residues (ATOM records): (download) 
    >2rhgA (A:)
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsli
eklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiieknlaspkqmlaelrs
fvsamkaasr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2rhgB (B:)
mttllnpyfgefggmyvpqilmpalnqleeafvsaqkdpefqaqfadllknyagrptalt
kcqnitagtrttlylkredllhggahktnqvlgqallakrmgkseiiaetgagqhgvasa
lasallglkcriymgakdverqspnvfrmrlmgaevipvhsgsatlkdacnealrdwsgs
yetahymlgtaagphpyptivrefqrmigeetkaqildkegrlpdaviacvgggsnaigm
fadfindtsvgligvepgghgietgehgaplkhgrvgiyfgmkapmmqtadgqieesysi
sagldfpsvgpqhaylnsigradyvsitddealeafktlcrhegiipalesshalahalk
mmreqpekeqllvvnlsgrgdkdiftvhdilkargei

    Sequence, based on observed residues (ATOM records): (download) 
    >2rhgB (B:)
ttllnpyfgefggmyvpqilmpalnqleeafvsaqkdpefqaqfadllknyagrptaltk
cqnitagtrttlylkredllhggahktnqvlgqallakrmgkseiiaetgagqhgvasal
asallglkcriynvfrmrlmgaevialrdwsgsyetahymlgtaagphpyptivrefqrm
igeetkaqildkegrlpdaviacvgggsnaigmfadfindtsvgligvepgghgietgeh
gaplkhgrvgiyfgmkapmmqtadgqieesysisagldfpsvgpqhaylnsigradyvsi
tddealeafktlcrhegiipalesshalahalkmmreqpekeqllvvnlsgrgdkdiftv
hdil