PDB entry 2rh4
View 2rh4 on RCSB PDB site
Description: Actinorhodin ketoreductase, actKR, with NADPH and Inhibitor Emodin
Class: oxidoreductase
Keywords: oxidoreductase, polyketide, actinorhodin, ketoreductase, combinatorial biosynthesis, short chain dehydrogenase/reductase
Deposited on
2007-10-05, released
2008-08-19
The last revision prior to the SCOPe 2.07 freeze date was dated
2013-11-20, with a file datestamp of
2013-11-15.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.179
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Actinorhodin Polyketide Ketoreductase
Species: Streptomyces coelicolor [TaxId:1902]
Gene: actIII
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d2rh4a_ - Chain 'B':
Compound: Actinorhodin Polyketide Ketoreductase
Species: Streptomyces coelicolor [TaxId:1902]
Gene: actIII
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d2rh4b2, d2rh4b3 - Heterogens: NDP, EMO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2rh4A (A:)
hhhhhhssglvprgshmatqdsevalvtgatsgigleiarrlgkeglrvfvcargeeglr
ttlkelreagveadgrtcdvrsvpeiealvaavverygpvdvlvnnagrpgggataelad
elwldvvetnltgvfrvtkqvlkaggmlergtgrivniastggkqgvvhaapysaskhgv
vgftkalglelartgitvnavcpgfvetpmaasvrehysdiwevsteeafdritarvpig
ryvqpsevaemvayligpgaaavtaqalnvcgglgny
Sequence, based on observed residues (ATOM records): (download)
>2rh4A (A:)
dsevalvtgatsgigleiarrlgkeglrvfvcargeeglrttlkelreagveadgrtcdv
rsvpeiealvaavverygpvdvlvnnagrpgggataeladelwldvvetnltgvfrvtkq
vlkaggmlergtgrivniastggkqgvvhaapysaskhgvvgftkalglelartgitvna
vcpgfvetpmaasvrehysdiwevsteeafdritarvpigryvqpsevaemvayligpga
aavtaqalnvcgglgny
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2rh4B (B:)
hhhhhhssglvprgshmatqdsevalvtgatsgigleiarrlgkeglrvfvcargeeglr
ttlkelreagveadgrtcdvrsvpeiealvaavverygpvdvlvnnagrpgggataelad
elwldvvetnltgvfrvtkqvlkaggmlergtgrivniastggkqgvvhaapysaskhgv
vgftkalglelartgitvnavcpgfvetpmaasvrehysdiwevsteeafdritarvpig
ryvqpsevaemvayligpgaaavtaqalnvcgglgny
Sequence, based on observed residues (ATOM records): (download)
>2rh4B (B:)
lvprgshmatqdsevalvtgatsgigleiarrlgkeglrvfvcargeeglrttlkelrea
gveadgrtcdvrsvpeiealvaavverygpvdvlvnnagrpgggataeladelwldvvet
nltgvfrvtkqvlkaggmlergtgrivniastggkqgvvhaapysaskhgvvgftkalgl
elartgitvnavcpgfvetpmaasvrehysdiwevsteeafdritarvpigryvqpseva
emvayligpgaaavtaqalnvcgglgny