PDB entry 2rgz

View 2rgz on RCSB PDB site
Description: Ensemble refinement of the protein crystal structure of human heme oxygenase-2 C127A (HO-2) with bound heme
Class: oxidoreductase
Keywords: Ensemble Refinement, Refinement Methodology Development, Structural Genomics Medical Relevance, Structural Genomics Community Request, HO-2, HEME Oxygenase, Endoplasmic reticulum, Iron, Metal-binding, Microsome, Oxidoreductase, Structural Genomics, Protein Structure Initiative, PSI, Center for Eukaryotic Structural Genomics, CESG
Deposited on 2007-10-05, released 2007-10-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.61 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heme oxygenase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: HMOX2, HO2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30519
      • engineered (126)
    Domains in SCOPe 2.08: d2rgza_
  • Chain 'B':
    Compound: Heme oxygenase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: HMOX2, HO2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30519
      • engineered (126)
    Domains in SCOPe 2.08: d2rgzb_
  • Heterogens: HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2rgzA (A:)
    msaevetsegvdesekknsgalekenqmrmadlsellkegtkeahdraentqfvkdflkg
    nikkelfklattalyftysaleeemernkdhpafaplyfpmelhrkealtkdmeyffgen
    weeqvqapkaaqkyverihyigqnepellvahaytrymgdlsggqvlkkvaqralklpst
    gegtqfylfenvdnaqqfkqlyrarmnaldlnmktkeriveeankafeynmqifneldqa
    gstlaretledgfpvhdgkgdmrk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2rgzA (A:)
    rmadlsellkegtkeahdraentqfvkdflkgnikkelfklattalyftysaleeemern
    kdhpafaplyfpmelhrkealtkdmeyffgenweeqvqapkaaqkyverihyigqnepel
    lvahaytrymgdlsggqvlkkvaqralklpstgegtqfylfenvdnaqqfkqlyrarmna
    ldlnmktkeriveeankafeynmqifneldqags
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2rgzB (B:)
    msaevetsegvdesekknsgalekenqmrmadlsellkegtkeahdraentqfvkdflkg
    nikkelfklattalyftysaleeemernkdhpafaplyfpmelhrkealtkdmeyffgen
    weeqvqapkaaqkyverihyigqnepellvahaytrymgdlsggqvlkkvaqralklpst
    gegtqfylfenvdnaqqfkqlyrarmnaldlnmktkeriveeankafeynmqifneldqa
    gstlaretledgfpvhdgkgdmrk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2rgzB (B:)
    madlsellkegtkeahdraentqfvkdflkgnikkelfklattalyftysaleeemernk
    dhpafaplyfpmelhrkealtkdmeyffgenweeqvqapkaaqkyverihyigqnepell
    vahaytrymgdlsggqvlkkvaqralklpstgegtqfylfenvdnaqqfkqlyrarmnal
    dlnmktkeriveeankafeynmqifneldqagstlaret