PDB entry 2rg6

View 2rg6 on RCSB PDB site
Description: Phenylalanine pyrrolotriazine p38 alpha map kinase inhibitor compound 11J
Class: transferase
Keywords: serine/threonine-protein kinase, kinase, transferase, p38 map kinase
Deposited on 2007-10-02, released 2008-01-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: 0.2
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2rg6a_
  • Heterogens: 287, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2rg6A (A:)
mahhhhhsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkk
lsrpfqsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadln
nivkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarh
tddemtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlkl
ilrlvgtpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsd
kritaaqalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppld
qeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >2rg6A (A:)
erptfyrqelnktiwevperyqnlspvggsvcaafdtktglrvavkklsrpfqsiihakr
tyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltddhv
qfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglaratrwyrapeimlnw
mhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarn
yiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpdde
pvadpydqsfesrdllidewksltydevisfvppp