PDB entry 2rf9

View 2rf9 on RCSB PDB site
Description: crystal structure of the complex between the egfr kinase domain and a mig6 peptide
Deposited on 2007-09-28, released 2007-12-04
The last revision was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Epidermal growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: EGFR, ERBB1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Epidermal growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: EGFR, ERBB1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: ERBB receptor feedback inhibitor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ERRFI1, MIG6
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: ERBB receptor feedback inhibitor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ERRFI1, MIG6
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2rf9A (A:)
gamgeapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreats
pkankeildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsq
yllnwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhae
ggkvpikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekger
lpqppictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsp
tdsnfyralmdeedmddvvdadeylipqqg

    Sequence, based on observed residues (ATOM records):
    >2rf9A (A:)
pnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelrepkankeild
eayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyllnwcvqi
akgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhagkvpikwmal
esilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppictidv
ymimvkcwmidadsrpkfreliiefskmardpqrylviqg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2rf9B (B:)
gamgeapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreats
pkankeildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsq
yllnwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhae
ggkvpikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekger
lpqppictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsp
tdsnfyralmdeedmddvvdadeylipqqg

    Sequence, based on observed residues (ATOM records):
    >2rf9B (B:)
qallrilketefkkikvlgsgafgtvykglwipekipvaikelrankeildeayvmasvd
nphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyllnwcvqiakgmnyled
rrlvhrdlaarnvlvktpqhvkitdfglakllgeyhagkvpikwmalesilhriythqsd
vwsygvtvwelmtfgskpydgipaseissilekgerlpqppictidvymimvkcwmidad
srpkfreliiefskmardpqrylviqgde

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2rf9C (C:)
gplgsrppkvppreplspsnsrtpspkslpsylngvmpptqsfapdpkyvsskalqrqns
egsas

    Sequence, based on observed residues (ATOM records):
    >2rf9C (C:)
kslpsylngvmpptqsfapdpkyvssk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2rf9D (D:)
gplgsrppkvppreplspsnsrtpspkslpsylngvmpptqsfapdpkyvsskalqrqns
egsas

    Sequence, based on observed residues (ATOM records):
    >2rf9D (D:)
slpsylngvmpptqsfapdpkyvssk