PDB entry 2ren

View 2ren on RCSB PDB site
Description: structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 angstroms resolution
Class: hydrolase(acid proteinase)
Keywords: hydrolase(acid proteinase)
Deposited on 1992-02-05, released 1994-01-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: renin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2rena_
  • Heterogens: NAG

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2renA (A:)
ltlgnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvy
hklfdasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfm
laefdgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlgg
sdpqhyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssie
klmealgakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlai
hamdippptgptwalgatfirkfytefdrrnnrigfalar

    Sequence, based on observed residues (ATOM records): (download) 
    >2renA (A:)
gnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcstacvyhklfda
sdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaefdg
vvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdslggqivlggsdpqhyegnfh
yinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmealgakkr
lfdyvvkcnegptlpdisfhlggkeytltsadyvfctlaihamdippptgptwalgatfi
rkfytefdrrnnrigfalar