PDB entry 2ram

View 2ram on RCSB PDB site
Description: a novel DNA recognition mode by nf-kb p65 homodimer
Class: transcription/DNA
Keywords: complex (transcription factor/DNA), DNA-binding, transcription regulation, activator nuclear protein, phosphorylation, conformation, transcription/DNA complex
Deposited on 1997-11-23, released 1998-05-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.213
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (transcription factor nf-kb p65)
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2rama1, d2rama2
  • Chain 'B':
    Compound: protein (transcription factor nf-kb p65)
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2ramb1, d2ramb2
  • Chain 'C':
    Compound: DNA (5'-d(*cp*gp*gp*cp*tp*gp*gp*ap*ap*ap*tp*(5iu)p*(5iu)p*cp*cp*ap*gp*cp*cp*g)-3')
  • Chain 'D':
    Compound: DNA (5'-d(*cp*gp*gp*cp*tp*gp*gp*ap*ap*ap*tp*(5iu)p*(5iu)p*cp*cp*ap*gp*cp*cp*g)-3')
  • Heterogens: DTV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ramA (A:)
pyveiieqpkqrgmrfrykcegrsagsipgerstdttkthptikingytgpgtvrislvt
kdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtnn
npfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnrapntaelkicr
vnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppya
dpslqapvrvsmqlrrpsdrelsepmefqylpd

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ramB (B:)
pyveiieqpkqrgmrfrykcegrsagsipgerstdttkthptikingytgpgtvrislvt
kdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtnn
npfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnrapntaelkicr
vnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppya
dpslqapvrvsmqlrrpsdrelsepmefqylpd

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.