PDB entry 2r9p

View 2r9p on RCSB PDB site
Description: Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor(BPTI)
Class: hydrolase/hydrolase inhibitor
Keywords: Human mesotrypsin, Serine protease, Bovine pancreatic trypsin inhibitor, BPTI, Alternative splicing, Calcium, Digestion, Hydrolase, Metal-binding, Secreted, Sulfation, Zymogen, Pharmaceutical, Protease inhibitor, Serine protease inhibitor, hydrolase/hydrolase inhibitor COMPLEX
Deposited on 2007-09-13, released 2007-12-11
The last revision prior to the SCOP 1.75 freeze date was dated 2008-02-26, with a file datestamp of 2008-02-22.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.17
AEROSPACI score: 0.73 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Trypsin-3
  Species: HOMO SAPIENS
  Gene: PRSS3, PRSS4, TRY3, TRY4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35030 (0-223)
    • engineered (176)
• Chain 'B':
  Compound: Trypsin-3
  Species: HOMO SAPIENS
  Gene: PRSS3, PRSS4, TRY3, TRY4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35030 (0-223)
    • engineered (176)
• Chain 'C':
  Compound: Trypsin-3
  Species: HOMO SAPIENS
  Gene: PRSS3, PRSS4, TRY3, TRY4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35030 (0-223)
    • engineered (176)
• Chain 'D':
  Compound: Trypsin-3
  Species: HOMO SAPIENS
  Gene: PRSS3, PRSS4, TRY3, TRY4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35030 (0-223)
    • engineered (176)
• Chain 'E':
  Compound: pancreatic trypsin inhibitor
  Species: Bos taurus
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00974 (0-57)
  Domains in SCOP 1.75: d2r9pe1
• Chain 'F':
  Compound: pancreatic trypsin inhibitor
  Species: Bos taurus
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00974 (0-57)
  Domains in SCOP 1.75: d2r9pf1
• Chain 'G':
  Compound: pancreatic trypsin inhibitor
  Species: Bos taurus
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00974 (0-57)
  Domains in SCOP 1.75: d2r9pg1
• Chain 'I':
  Compound: pancreatic trypsin inhibitor
  Species: Bos taurus
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00974 (0-57)
  Domains in SCOP 1.75: d2r9pi1
• Heterogens: SO4, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2r9pE (E:)
  rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga
  

  
  
• Chain 'F':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2r9pF (F:)
  rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga
  

  
  
• Chain 'G':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2r9pG (G:)
  rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga
  

  
  
• Chain 'I':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2r9pI (I:)
  rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga