PDB entry 2r9f

View 2r9f on RCSB PDB site
Description: Calpain 1 proteolytic core inactivated by ZLAK-3002, an alpha-ketoamide
Class: hydrolase
Keywords: PROTEASE, PEPTIDASE, INHIBITOR, ALPHA-KETOAMIDE, Hydrolase, Membrane, Thiol protease
Deposited on 2007-09-12, released 2008-08-26
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.191
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Calpain-1 catalytic subunit
    Species: Rattus norvegicus
    Gene: Capn1, Cls1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2r9fa_
  • Heterogens: CA, CL, K2Z, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2r9fA (A:)
mglgrhenaikylgqdyenlrarclqngvlfqddafppvshslgfkelgpnssktygikw
krptellsnpqfivdgatrtdicqgalgdcwllaaiasltlnetilhrvvpygqsfqegy
agifhfqlwqfgewvdvvvddllptkdgklvfvhsaqgnefwsallekayakvngsyeal
sggctseafedftggvtewydlqkapsdlyqiilkalergsllgcsinisdirdleaitf
knlvrghaysvtdakqvtyqgqrvnlirmrnpwgevewkgpwsdnsyewnkvdpyereql
rvkmedgefwmsfrdfireftkleicnltpdlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2r9fA (A:)
naikylgqdyenlrarclqngvlfqddafppvshslgfkelgpnssktygikwkrptell
snpqfivdgatrtdicqgalgdcwllaaiasltlnetilhrvvpygqsfqegyagifhfq
lwqfgewvdvvvddllptkdgklvfvhsaqgnefwsallekayakvngsyealsggctse
afedftggvtewydlqkapsdlyqiilkalergsllgcsinisdirdleaitfknlvrgh
aysvtdakqvtyqgqrvnlirmrnpwgevewkgpwsdnsyewnkvdpyereqlrvkmedg
efwmsfrdfireftkleicnlt