PDB entry 2r9c
View 2r9c on RCSB PDB site
Description: Calpain 1 proteolytic core inactivated by ZLAK-3001, an alpha-ketoamide
Class: hydrolase
Keywords: PROTEASE, PEPTIDASE, INHIBITOR, ALPHA-KETOAMIDE, Calcium, Cytoplasm, Hydrolase, Membrane, Thiol protease
Deposited on
2007-09-12, released
2008-08-26
The last revision prior to the SCOP 1.75 freeze date was dated
2008-09-23, with a file datestamp of
2008-09-19.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.158
AEROSPACI score: 0.63
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Calpain-1 catalytic subunit
Species: Rattus norvegicus
Gene: Capn1, Cls1
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2r9ca1 - Heterogens: CA, CL, GRD, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2r9cA (A:)
mglgrhenaikylgqdyenlrarclqngvlfqddafppvshslgfkelgpnssktygikw
krptellsnpqfivdgatrtdicqgalgdcwllaaiasltlnetilhrvvpygqsfqegy
agifhfqlwqfgewvdvvvddllptkdgklvfvhsaqgnefwsallekayakvngsyeal
sggctseafedftggvtewydlqkapsdlyqiilkalergsllgcsinisdirdleaitf
knlvrghaysvtdakqvtyqgqrvnlirmrnpwgevewkgpwsdnsyewnkvdpyereql
rvkmedgefwmsfrdfireftkleicnltpdlehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2r9cA (A:)
naikylgqdyenlrarclqngvlfqddafppvshslgfkelgpnssktygikwkrptell
snpqfivdgatrtdicqgalgdcwllaaiasltlnetilhrvvpygqsfqegyagifhfq
lwqfgewvdvvvddllptkdgklvfvhsaqgnefwsallekayakvngsyealsggctse
afedftggvtewydlqkapsdlyqiilkalergsllgcsinisdirdleaitfknlvrgh
aysvtdakqvtyqgqrvnlirmrnpwgevewkgpwsdnsyewnkvdpyereqlrvkmedg
efwmsfrdfireftkleicnlt