PDB entry 2r6k

View 2r6k on RCSB PDB site
Description: Crystal structure of an I71V hGSTA1-1 mutant in complex with S-hexylglutathione
Class: transferase
Keywords: human Alpha class glutathione transferase 1-1, s-hexyl-glutathione, X-ray crystal structure, TRANSFERASE
Deposited on 2007-09-06, released 2008-08-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-09-29, with a file datestamp of 2010-09-24.
Experiment type: XRAY
Resolution: 2.51 Å
R-factor: 0.211
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutathione s-transferase a1
    Species: HOMO SAPIENS
    Gene: GSTA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08263 (Start-221)
      • engineered (70)
    Domains in SCOPe 2.06: d2r6ka1, d2r6ka2
  • Chain 'B':
    Compound: glutathione s-transferase a1
    Species: HOMO SAPIENS
    Gene: GSTA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08263 (Start-221)
      • engineered (70)
    Domains in SCOPe 2.06: d2r6kb1, d2r6kb2
  • Heterogens: GTX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2r6kA (A:)
maekpklhyfnargrmestrwllaaagvefeekfiksaedldklrndgylmfqqvpmvei
dgmklvqtravlnyiaskynlygkdikeralidmyiegiadlgemilllpvcppeekdak
lalikekiknryfpafekvlkshgqdylvgnklsradihlvellyyveeldsslissfpl
lkalktrisnlptvkkflqpgsprkppmdeksleearkifrf

    Sequence, based on observed residues (ATOM records): (download) 
    >2r6kA (A:)
aekpklhyfnargrmestrwllaaagvefeekfiksaedldklrndgylmfqqvpmveid
gmklvqtravlnyiaskynlygkdikeralidmyiegiadlgemilllpvcppeekdakl
alikekiknryfpafekvlkshgqdylvgnklsradihlvellyyveeldsslissfpll
kalktrisnlptvkkflqpgsprkppmdeksleearkifrf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2r6kB (B:)
maekpklhyfnargrmestrwllaaagvefeekfiksaedldklrndgylmfqqvpmvei
dgmklvqtravlnyiaskynlygkdikeralidmyiegiadlgemilllpvcppeekdak
lalikekiknryfpafekvlkshgqdylvgnklsradihlvellyyveeldsslissfpl
lkalktrisnlptvkkflqpgsprkppmdeksleearkifrf

    Sequence, based on observed residues (ATOM records): (download) 
    >2r6kB (B:)
kpklhyfnargrmestrwllaaagvefeekfiksaedldklrndgylmfqqvpmveidgm
klvqtravlnyiaskynlygkdikeralidmyiegiadlgemilllpvcppeekdaklal
ikekiknryfpafekvlkshgqdylvgnklsradihlvellyyveeldsslissfpllka
lktrisnlptvkkflqpgsprkppmdeksleearkifrf