PDB entry 2r5n

View 2r5n on RCSB PDB site
Description: Crystal structure of transketolase from Escherichia coli in noncovalent complex with acceptor aldose ribose 5-phosphate
Class: transferase
Keywords: thiamin catalysis, sugar phosphates, acceptor, near attack conformation, cyclic, acyclic, ribose-5-phospate, pyranose, Metal-binding, Thiamine pyrophosphate, Transferase
Deposited on 2007-09-04, released 2007-11-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.164
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transketolase 1
    Species: Escherichia coli [TaxId:562]
    Gene: tktA, tkt
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27302 (Start-662)
      • expression tag (663-666)
    Domains in SCOPe 2.07: d2r5na1, d2r5na2, d2r5na3, d2r5na4
  • Chain 'B':
    Compound: Transketolase 1
    Species: Escherichia coli [TaxId:562]
    Gene: tktA, tkt
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27302 (Start-662)
      • expression tag (663)
    Domains in SCOPe 2.07: d2r5nb1, d2r5nb2, d2r5nb3, d2r5nb4
  • Heterogens: R5P, CA, TPP, EDO, RP5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2r5nA (A:)
mssrkelanairalsmdavqkaksghpgapmgmadiaevlwrdflkhnpqnpswadrdrf
vlsnghgsmliysllhltgydlpmeelknfrqlhsktpghpevgytagvetttgplgqgi
anavgmaiaektlaaqfnrpghdivdhytyafmgdgcmmegishevcslagtlklgklia
fyddngisidghvegwftddtamrfeaygwhvirdidghdaasikraveearavtdkpsl
lmcktiigfgspnkagthdshgaplgdaeialtreqlgwkyapfeipseiyaqwdakeag
qakesawnekfaayakaypqeaaeftrrmkgempsdfdakakefiaklqanpakiasrka
sqnaieafgpllpeflggsadlapsnltlwsgskainedaagnyihygvrefgmtaiang
islhggflpytstflmfveyarnavrmaalmkqrqvmvythdsiglgedgpthqpveqva
slrvtpnmstwrpcdqvesavawkygverqdgptalilsrqnlaqqerteeqlaniargg
yvlkdcagqpelifiatgsevelavaayekltaegvkarvvsmpstdafdkqdaayresv
lpkavtarvaveagiadywykyvglngaivgmttfgesapaellfeefgftvdnvvakak
ellhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2r5nA (A:)
ssrkelanairalsmdavqkaksghpgapmgmadiaevlwrdflkhnpqnpswadrdrfv
lsnghgsmliysllhltgydlpmeelknfrqlhsktpghpevgytagvetttgplgqgia
navgmaiaektlaaqfnrpghdivdhytyafmgdgcmmegishevcslagtlklgkliaf
yddngisidghvegwftddtamrfeaygwhvirdidghdaasikraveearavtdkpsll
mcktiigfgspnkagthdshgaplgdaeialtreqlgwkyapfeipseiyaqwdakeagq
akesawnekfaayakaypqeaaeftrrmkgempsdfdakakefiaklqanpakiasrkas
qnaieafgpllpeflggsadlapsnltlwsgskainedaagnyihygvrefgmtaiangi
slhggflpytstflmfveyarnavrmaalmkqrqvmvythdsiglgedgpthqpveqvas
lrvtpnmstwrpcdqvesavawkygverqdgptalilsrqnlaqqerteeqlaniarggy
vlkdcagqpelifiatgsevelavaayekltaegvkarvvsmpstdafdkqdaayresvl
pkavtarvaveagiadywykyvglngaivgmttfgesapaellfeefgftvdnvvakake
llhhhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2r5nB (B:)
mssrkelanairalsmdavqkaksghpgapmgmadiaevlwrdflkhnpqnpswadrdrf
vlsnghgsmliysllhltgydlpmeelknfrqlhsktpghpevgytagvetttgplgqgi
anavgmaiaektlaaqfnrpghdivdhytyafmgdgcmmegishevcslagtlklgklia
fyddngisidghvegwftddtamrfeaygwhvirdidghdaasikraveearavtdkpsl
lmcktiigfgspnkagthdshgaplgdaeialtreqlgwkyapfeipseiyaqwdakeag
qakesawnekfaayakaypqeaaeftrrmkgempsdfdakakefiaklqanpakiasrka
sqnaieafgpllpeflggsadlapsnltlwsgskainedaagnyihygvrefgmtaiang
islhggflpytstflmfveyarnavrmaalmkqrqvmvythdsiglgedgpthqpveqva
slrvtpnmstwrpcdqvesavawkygverqdgptalilsrqnlaqqerteeqlaniargg
yvlkdcagqpelifiatgsevelavaayekltaegvkarvvsmpstdafdkqdaayresv
lpkavtarvaveagiadywykyvglngaivgmttfgesapaellfeefgftvdnvvakak
ellhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2r5nB (B:)
ssrkelanairalsmdavqkaksghpgapmgmadiaevlwrdflkhnpqnpswadrdrfv
lsnghgsmliysllhltgydlpmeelknfrqlhsktpghpevgytagvetttgplgqgia
navgmaiaektlaaqfnrpghdivdhytyafmgdgcmmegishevcslagtlklgkliaf
yddngisidghvegwftddtamrfeaygwhvirdidghdaasikraveearavtdkpsll
mcktiigfgspnkagthdshgaplgdaeialtreqlgwkyapfeipseiyaqwdakeagq
akesawnekfaayakaypqeaaeftrrmkgempsdfdakakefiaklqanpakiasrkas
qnaieafgpllpeflggsadlapsnltlwsgskainedaagnyihygvrefgmtaiangi
slhggflpytstflmfveyarnavrmaalmkqrqvmvythdsiglgedgpthqpveqvas
lrvtpnmstwrpcdqvesavawkygverqdgptalilsrqnlaqqerteeqlaniarggy
vlkdcagqpelifiatgsevelavaayekltaegvkarvvsmpstdafdkqdaayresvl
pkavtarvaveagiadywykyvglngaivgmttfgesapaellfeefgftvdnvvakake
llh