PDB entry 2r5a

View 2r5a on RCSB PDB site
Description: Crystal Structure of the two MBT repeats from Sex-Comb on Midleg (SCM) in complex with methyl lysine
Class: transcription
Keywords: MBT repeat, Polycomb, Sex Comb on Midleg, SCM, MBT, Chromatin regulator, Developmental protein, Metal-binding, Nucleus, Repressor, Transcription, Transcription regulation
Deposited on 2007-09-03, released 2007-10-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.175
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polycomb protein Scm
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Scm
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9VHA0 (4-End)
      • expression tag (3)
      • engineered (106)
    Domains in SCOPe 2.08: d2r5aa1, d2r5aa2, d2r5aa3
  • Heterogens: MLZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2r5aA (A:)
gamafdwdayleetgseaapakcfkqaqnppnndfkigmklealdprnvtstciatvvgv
lgsrlrlrldgsdsqndfwrlvdsteihaighceknggmlqpplgfcmnasswpgylcki
lnnamvapeeifqpeppepeenlfkvgqkleavdkknpqliccatvdaikddqihvtfdg
wrgafdywcnyrsrdifpagwcarschpmqppghksrmdsssskqrcprprytvvaesea
mvpaspatahfhpnckggpfinnsk

    Sequence, based on observed residues (ATOM records): (download) 
    >2r5aA (A:)
afdwdayleetgseaapakcfkqaqnppnndfkigmklealdprnvtstciatvvgvlgs
rlrlrldgsdsqndfwrlvdsteihaighceknggmlqpplgfcmnasswpgylckilnn
amvapeeifqpeppepeenlfkvgqkleavdkknpqliccatvdaikddqihvtfdgwrg
afdywcnyrsrdifpagwcarschpmqppghk