PDB entry 2r53

View 2r53 on RCSB PDB site
Description: Crystal structure analysis of Bone Morphogenetic Protein-6 variant B2 (B2-BMP-6)
Class: cytokine
Keywords: BMP6, Vgr, TGF-beta ligand, Chondrogenesis, Cleavage on pair of basic residues, Cytokine, Developmental protein, Differentiation, Glycoprotein, Growth factor, Osteogenesis, Secreted
Deposited on 2007-09-03, released 2008-01-15
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.259
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bone morphogenetic protein 6
    Species: Homo sapiens [TaxId:9606]
    Gene: BMP6, VGR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22004 (13-115)
      • see remark 999 (9-12)
    Domains in SCOPe 2.03: d2r53a_
  • Chain 'B':
    Compound: Bone morphogenetic protein 6
    Species: Homo sapiens [TaxId:9606]
    Gene: BMP6, VGR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22004 (13-115)
      • see remark 999 (9-12)
    Domains in SCOPe 2.03: d2r53b_
  • Heterogens: MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2r53A (A:)
maqakhkqrkrlkacrkhelyvsfqdlgwqdwiiapkgyaanycdgecsfplnahmnatn
haivqtlvhlmnpeyvpkpccaptklnaisvlyfddnsnvilkkyrnmvvracgch

    Sequence, based on observed residues (ATOM records): (download) 
    >2r53A (A:)
krlkacrkhelyvsfqdlgwqdwiiapkgyaanycdgecsfplnahmnatnhaivqtlvh
lmnpeyvpkpccaptklnaisvlyfddnsnvilkkyrnmvvracgch

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2r53B (B:)
maqakhkqrkrlkacrkhelyvsfqdlgwqdwiiapkgyaanycdgecsfplnahmnatn
haivqtlvhlmnpeyvpkpccaptklnaisvlyfddnsnvilkkyrnmvvracgch

    Sequence, based on observed residues (ATOM records): (download) 
    >2r53B (B:)
krlkacrkhelyvsfqdlgwqdwiiapkgyaanycdgecsfplnahmnatnhaivqtlvh
lmnpeyvpkpccaptklnaisvlyfddnsnvilkkyrnmvvracgch