PDB entry 2r37

View 2r37 on RCSB PDB site
Description: Crystal structure of human glutathione peroxidase 3 (selenocysteine to glycine mutant)
Class: oxidoreductase
Keywords: GLUTATHIONE, PEROXIDASE, PLASMA, STRUCTURAL GENOMICS CONSORTIUM, SGC, Oxidoreductase, Secreted, Selenium, Selenocysteine
Deposited on 2007-08-29, released 2007-09-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutathione peroxidase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: GPX3, GPXP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22352 (Start-199)
      • engineered (49)
      • expression tag (200-204)
    Domains in SCOPe 2.08: d2r37a1, d2r37a2
  • Chain 'B':
    Compound: Glutathione peroxidase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: GPX3, GPXP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22352 (Start-199)
      • engineered (49)
    Domains in SCOPe 2.08: d2r37b_
  • Heterogens: CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2r37A (A:)
mqekskmdchggisgtiyeygaltidgeeyipfkqyagkyvlfvnvasyggltgqyieln
alqeelapfglvilgfpcnqfgkqepgenseilptlkyvrpgggfvpnfqlfekgdvnge
keqkfytflknscpptsellgtsdrlfwepmkvhdirwnfekflvgpdgipimrwhhrtt
vsnvkmdilsymrrqaalgvaenlyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2r37A (A:)
gtiyeygaltidgeeyipfkqyagkyvlfvnvasyggltgqyielnalqeelapfglvil
gfpcnqfgkqepgenseilptlkyvrpgggfvpnfqlfekgdvngekeqkfytflknscp
ptsellgtsdrlfwepmkvhdirwnfekflvgpdgipimrwhhrttvsnvkmdilsymrr
qaalgvaenly

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2r37B (B:)
mqekskmdchggisgtiyeygaltidgeeyipfkqyagkyvlfvnvasyggltgqyieln
alqeelapfglvilgfpcnqfgkqepgenseilptlkyvrpgggfvpnfqlfekgdvnge
keqkfytflknscpptsellgtsdrlfwepmkvhdirwnfekflvgpdgipimrwhhrtt
vsnvkmdilsymrrqaalgvaenlyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2r37B (B:)
isgtiyeygaltidgeeyipfkqyagkyvlfvnvasyggltgqyielnalqeelapfglv
ilgfpcnqfgkqepgenseilptlkyvrpgggfvpnfqlfekgdvngekeqkfytflkns
cpptsellgtsdrlfwepmkvhdirwnfekflvgpdgipimrwhhrttvsnvkmdilsym
rrqaalgv