PDB entry 2r0z

View 2r0z on RCSB PDB site
Description: PFA1 FAB complexed with GripI peptide fragment
Class: immune system
Keywords: immunoglobulin; Alzheimer disease; amyloid, IMMUNE SYSTEM
Deposited on 2007-08-21, released 2007-10-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: IgG2a Fab fragment heavy chain, Fd portion
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2R0Z (0-222)
    Domains in SCOPe 2.08: d2r0zh_
  • Chain 'L':
    Compound: IgG2a Fab fragment light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A2NHM3 (0-218)
      • conflict (26)
      • conflict (100)
      • conflict (104)
      • conflict (110)
      • modified residue (218)
    Domains in SCOPe 2.08: d2r0zl1, d2r0zl2
  • Chain 'Q':
    Compound: GripI peptide fragment
    Database cross-references and differences (RAF-indexed):
    • PDB 2R0Z (0-5)
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2r0zH (H:)
qvtlkesgpgilkpsqtlsltcsfsgfslstsgmgvgwirqpsgkglewlahiwwdddrs
ynpslksqltiskdtsrnqvflritsvdtadtatyycvrrahttvlgdwfaywgqgtlvt
vsaakttapsvyplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpall
qsdlytlsssstvtsstwpsqsitcnvahpasstkvdkkiepr

    Sequence, based on observed residues (ATOM records): (download) 
    >2r0zH (H:)
qvtlkesgpgilkpsqtlsltcsfsgfslstsgmgvgwirqpsgkglewlahiwwdddrs
ynpslksqltiskdtsrnqvflritsvdtadtatyycvrrahttvlgdwfaywgqgtlvt
vsaakttapsvyplapvcssvtlgclvkgyfpepvtltwnsglssgvhtfpallqdlytl
sssstvtsstwpsqsitcnvahpasstkvdkkiepr

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2r0zL (L:)
dvlmtqtplslpvslgdqasiscrssqsivhsngntylewylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyycfqgshvpltfgagtklelkradaaptv
sifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysm
sstltltkdeyerhnsytceathktstspivksfnrnec

  • Chain 'Q':
    No sequence available.