PDB entry 2r0u
View 2r0u on RCSB PDB site
Description: Crystal Structure of Chek1 in Complex with Inhibitor 54
Class: transferase
Keywords: Chek1, Kinase, cell cycle check point, ATP-binding, Cytoplasm, DNA damage, DNA repair, Nucleotide-binding, Nucleus, Phosphorylation, Polymorphism, Serine/threonine-protein kinase, Transferase, Ubl conjugation
Deposited on
2007-08-21, released
2007-10-30
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.197
AEROSPACI score: 0.45
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Serine/threonine-protein kinase Chk1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2r0ua_ - Heterogens: M54, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2r0uA (A:)
mavpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicink
mlnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvy
lhgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellk
rrefhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsapla
llhkilvenpsaritipdikkdrwynkplkkgakrprvtsggvsespsgfskhiqsnldf
spvnsasrtpgsgwskehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2r0uA (A:)
avpfvedwdlvqtlgegevqlavnrvteeavavkivdmknikkeicinkmlnhenvvkfy
ghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdi
kpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdv
wscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenps
aritipdikkdrwynkplkkgakrprvts