PDB entry 2qy0
View 2qy0 on RCSB PDB site
Description: Active dimeric structure of the catalytic domain of C1r reveals enzyme-product like contacts
Class: hydrolase
Keywords: complement, serine protease, beta barrel, Complement pathway, EGF-like domain, Glycoprotein, Hydrolase, Hydroxylation, Immune response, Innate immunity, Phosphorylation, Sushi
Deposited on
2007-08-13, released
2008-02-05
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.213
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Complement C1r subcomponent
Species: Homo sapiens [TaxId:9606]
Gene: C1R
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2qy0a1, d2qy0a2, d2qy0a3 - Chain 'B':
Compound: Complement C1r subcomponent
Species: Homo sapiens [TaxId:9606]
Gene: C1R
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2qy0b_ - Chain 'C':
Compound: Complement C1r subcomponent
Species: Homo sapiens [TaxId:9606]
Gene: C1R
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2qy0c1, d2qy0c2, d2qy0c3 - Chain 'D':
Compound: Complement C1r subcomponent
Species: Homo sapiens [TaxId:9606]
Gene: C1R
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2qy0d_ - Heterogens: GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2qy0A (A:)
stqacpqpktldeftiiqnlqpqyqfrdyfiatckqgyqliegnqvlhsftavcqddgtw
hramprckikdcgqprnlpngdfrytttmgvntykariqyychepyykmqtragsreseq
gvytctaqgiwkneqkgekiprclpvcgkpvnpveqrqr
Sequence, based on observed residues (ATOM records): (download)
>2qy0A (A:)
qacpqpktldeftiiqnlqpqyqfrdyfiatckqgyqliegnqvlhsftavcqddgtwhr
amprckikdcgqprnlpngdfrytttmgvntykariqyychepyykmqtrreseqgvytc
taqgiwkneqkgekiprclpvcgkpvnpveqrqr
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2qy0B (B:)
iiggqkakmgnfpwqvftnihgrgggallgdrwiltaahtlypkeheaqsnasldvflgh
tnveelmklgnhpirrvsvhpdyrqdesynfegdiallelensvtlgpnllpiclpdndt
fydlglmgyvsgfgvmeekiahdlrfvrlpvanpqacenwlrgknrmdvfsqnmfcaghp
slkqdacqgdsggvfavrdpntdrwvatgivswgigcsrgygfytkvlnyvdwikkemee
ed
Sequence, based on observed residues (ATOM records): (download)
>2qy0B (B:)
iiggqkakmgnfpwqvftnihgrgggallgdrwiltaahtlypkeheasldvflghtnve
elmklgnhpirrvsvhpdyrqdesynfegdiallelensvtlgpnllpiclpdndtfydl
glmgyvsgfgvmeekiahdlrfvrlpvanpqacenwlrgknrmdvfsqnmfcaghpslkq
dacqgdsggvfavrdpntdrwvatgivswgigcsrgygfytkvlnyvdwikkemee
- Chain 'C':
Sequence, based on SEQRES records: (download)
>2qy0C (C:)
stqacpqpktldeftiiqnlqpqyqfrdyfiatckqgyqliegnqvlhsftavcqddgtw
hramprckikdcgqprnlpngdfrytttmgvntykariqyychepyykmqtragsreseq
gvytctaqgiwkneqkgekiprclpvcgkpvnpveqrqr
Sequence, based on observed residues (ATOM records): (download)
>2qy0C (C:)
qacpqpktldeftiiqnlqpqyqfrdyfiatckqgyqliegnqvlhsftavcqddgtwhr
amprckikdcgqprnlpngdfrytttmgvntykariqyychepyykmqtreseqgvytct
aqgiwkneqkgekiprclpvcgkpvnpveqrqr
- Chain 'D':
Sequence, based on SEQRES records: (download)
>2qy0D (D:)
iiggqkakmgnfpwqvftnihgrgggallgdrwiltaahtlypkeheaqsnasldvflgh
tnveelmklgnhpirrvsvhpdyrqdesynfegdiallelensvtlgpnllpiclpdndt
fydlglmgyvsgfgvmeekiahdlrfvrlpvanpqacenwlrgknrmdvfsqnmfcaghp
slkqdacqgdsggvfavrdpntdrwvatgivswgigcsrgygfytkvlnyvdwikkemee
ed
Sequence, based on observed residues (ATOM records): (download)
>2qy0D (D:)
iiggqkakmgnfpwqvftnihgrgggallgdrwiltaahtlypkehsnasldvflghtnv
eelmklgnhpirrvsvhpdyrqdesynfegdiallelensvtlgpnllpiclpdndtfyd
lglmgyvsgfgvmeekiahdlrfvrlpvanpqacenwlrgknrmdvfsqnmfcaghpslk
qdacqgdsggvfavrdpntdrwvatgivswgigcsrgygfytkvlnyvdwikkemee