PDB entry 2qxv

View 2qxv on RCSB PDB site
Description: Structural basis of EZH2 recognition by EED
Deposited on 2007-08-13, released 2007-08-28
The last revision was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: 0.185
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Embryonic ectoderm development
    Species: Mus musculus [TaxId:10090]
    Gene: hEED
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Enhancer of zeste homolog 2
    Species: Mus musculus [TaxId:10090]
    Gene: Ezh2, Enx1h
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2qxvA (A:)
    sfkcvnslkedhnqplfgvqfnwhskegdplvfatvgsnrvtlyechsqgeirllqsyvd
    adadenfytcawtydsntshpllavagsrgiiriinpitmqcikhyvghgnainelkfhp
    rdpnlllsvskdhalrlwniqtdtlvaifggveghrdevlsadydllgekimscgmdhsl
    klwrinskrmmnaikesydynpnktnrpfisqkihfpdfstrdihrnyvdcvrwlgdlil
    skscenaivcwkpgkmeddidkikpsesnvtilgrfdysqcdiwymrfsmdfwqkmlalg
    nqvgklyvwdlevedphkakcttlthhkcgaairqtsfsrdssiliavcddasiwrwdrl
    r
    

    Sequence, based on observed residues (ATOM records):
    >2qxvA (A:)
    fkcvnslkedhnqplfgvqfnwhskegdplvfatvgsnrvtlyechsqgeirllqsyvda
    dadenfytcawtydsntshpllavagsrgiiriinpitmqcikhyvghgnainelkfhpr
    dpnlllsvskdhalrlwniqtdtlvaifggveghrdevlsadydllgekimscgmdhslk
    lwrinskrmmnaikesydynfisqkihfpdfstrdihrnyvdcvrwlgdlilskscenai
    vcwkpgkmeddidkikpsesnvtilgrfdysqcdiwymrfsmdfwqkmlalgnqvgklyv
    wdlevedphkakcttlthhkcgaairqtsfsrdssiliavcddasiwrwdrl
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2qxvB (B:)
    ktmfssnrqkilertetlnqewkqrriqpv
    

    Sequence, based on observed residues (ATOM records):
    >2qxvB (B:)
    tmfssnrqkilertetlnqewkqrriqpv