PDB entry 2qr1

View 2qr1 on RCSB PDB site
Description: Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with ADP
Class: transferase
Keywords: AMPK, ADP, ATP-binding, Kinase, Nucleotide-binding, Serine/threonine-protein kinase, Transferase, CBS domain
Deposited on 2007-07-27, released 2007-10-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.211
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: SNF1-like protein kinase ssp2
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: ssp2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qr1a_
  • Chain 'B':
    Compound: SPCC1919.03c protein
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qr1b_
  • Chain 'C':
    Compound: SNF1-like protein kinase ssp2
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Gene: ssp2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qr1c_
  • Chain 'D':
    Compound: SPCC1919.03c protein
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qr1d_
  • Chain 'E':
    Compound: Protein C1556.08c
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qr1e1, d2qr1e2
  • Chain 'G':
    Compound: Protein C1556.08c
    Species: Schizosaccharomyces pombe [TaxId:4896]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q10343 (2-333)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d2qr1g1, d2qr1g2, d2qr1g3
  • Heterogens: ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qr1A (A:)
sqstrkksrrnkwhfgvrcrgdapeillavyralqragaqftvpkpvngkyrsdmytiks
rweiphckregkntyayielqlyevmpgcfmldvksngykdiyshpertadhgmddlkss
fpfldlcamlvcklfsa

    Sequence, based on observed residues (ATOM records): (download) 
    >2qr1A (A:)
kwhfgvrcrgdapeillavyralqragaqftvpkpvngkyrsdmytiksrweiphckreg
kntyayielqlyevmpgcfmldvksngykdiyshdlkssfpfldlcamlvcklfsa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qr1B (B:)
mseseqysteipafltsntlqelklpkppslpphlekcilnsntaykedqsvlpnpnhvl
lnhlaaantqlgvlalsattryhrkyvttamfknfdv

    Sequence, based on observed residues (ATOM records): (download) 
    >2qr1B (B:)
qysteipafltsntlqelklpkppslpphlekcilnsntaykedqsvlpnpnhvllnhla
aantqlgvlalsattryhrkyvttamfknfd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2qr1C (C:)
sqstrkksrrnkwhfgvrcrgdapeillavyralqragaqftvpkpvngkyrsdmytiks
rweiphckregkntyayielqlyevmpgcfmldvksngykdiyshpertadhgmddlkss
fpfldlcamlvcklfsa

    Sequence, based on observed residues (ATOM records): (download) 
    >2qr1C (C:)
nkwhfgvrcrgdapeillavyralqragaqftvpkpvngkyrsdmytiksrweiphckre
gkntyayielqlyevmpgcfmldvksngykdikssfpfldlcamlvcklfsa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2qr1D (D:)
mseseqysteipafltsntlqelklpkppslpphlekcilnsntaykedqsvlpnpnhvl
lnhlaaantqlgvlalsattryhrkyvttamfknfdv

    Sequence, based on observed residues (ATOM records): (download) 
    >2qr1D (D:)
qysteipafltsntlqelklpkppslpphlekcilnsntaykedqsvlpnpnhvllnhla
aantqlgvlalsattryhrkyvttamfknfd

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2qr1E (E:)
amdvqetqkgalkeiqafirsrtsydvlptsfrlivfdvtlfvktslslltlnnivsapl
wdseankfaglltmadfvnvikyyyqsssfpeaiaeidkfrllglreverkigaippeti
yvhpmhslmdaclamsksrarriplidvdgetgsemivsvltqyrilkfismncketaml
rvplnqmtigtwsnlatasmetkvydvikmlaeknisavpivnsegtllnvyesvdvmhl
iqdgdysnldlsvgeallkrpanfdgvhtcratdrldgifdaikhsrvhrlfvvdenlkl
egilsladilnyiiydktttpgvpeqtdnfesav

    Sequence, based on observed residues (ATOM records): (download) 
    >2qr1E (E:)
dvqetqkgalkeiqafirsrtsydvlptsfrlivfdvtlfvktslslltlnnivsaplwd
seankfaglltmadfvnvikyyyqsssfpeaiaeidkfrllglreverkigaippetiyv
hpmhslmdaclamsksrarriplidvdgetgsemivsvltqyrilkfismncketamlrv
plnqmtigtwsnlatasmetkvydvikmlaeknisavpivnsegtllnvyesvdvmhliq
dgdysnldlsvgeallkrpanfdgvhtcratdrldgifdaikhsrvhrlfvvdenlkleg
ilsladilnyiiydkttdnfesav

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2qr1G (G:)
amdvqetqkgalkeiqafirsrtsydvlptsfrlivfdvtlfvktslslltlnnivsapl
wdseankfaglltmadfvnvikyyyqsssfpeaiaeidkfrllglreverkigaippeti
yvhpmhslmdaclamsksrarriplidvdgetgsemivsvltqyrilkfismncketaml
rvplnqmtigtwsnlatasmetkvydvikmlaeknisavpivnsegtllnvyesvdvmhl
iqdgdysnldlsvgeallkrpanfdgvhtcratdrldgifdaikhsrvhrlfvvdenlkl
egilsladilnyiiydktttpgvpeqtdnfesav

    Sequence, based on observed residues (ATOM records): (download) 
    >2qr1G (G:)
amdvqetqkgalkeiqafirsrtsydvlptsfrlivfdvtlfvktslslltlnnivsapl
wdseankfaglltmadfvnvikyyyqsssfpeaiaeidkfrllglreverkigaippeti
yvhpmhslmdaclamsksrarriplidvdgetgsemivsvltqyrilkfismncketaml
rvplnqmtigtwsnlatasmetkvydvikmlaeknisavpivnsegtllnvyesvdvmhl
iqdgdysnldlsvgeallkrpanfdgvhtcratdrldgifdaikhsrvhrlfvvdenlkl
egilsladilnyiiydkdnfesav