PDB entry 2qql

View 2qql on RCSB PDB site
Description: Neuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking Fab
Class: signaling protein
Keywords: VEGF receptor, semaphorin receptor, Phage-Derived Antibody, Developmental protein, Differentiation, Glycoprotein, Membrane, Neurogenesis, Transmembrane, HORMONE, SIGNALING PROTEIN
Deposited on 2007-07-26, released 2007-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuropilin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: NRP2, VEGF165R2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60462 (Start-572)
      • expression tag (576-578)
  • Chain 'H':
    Compound: antibody heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2QQL (0-End)
    Domains in SCOPe 2.08: d2qqlh_
  • Chain 'L':
    Compound: Antibody Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2QQL (0-213)
    Domains in SCOPe 2.08: d2qqll1, d2qqll2

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2qqlH (H:)
evqlvesggglvqpggslrlscaasgftisgygihwvrqapgkglewvayiypdsgytdy
adsvkgrftisadtskntaylqmnslraedtavyycaredfrnrrrlwyvmdywgqgtlv
tvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >2qqlH (H:)
evqlvesggglvqpggslrlscaasgftisgygihwvrqapgkglewvayiypdsgytdy
adsvkgrftisadtskntaylqmnslraedtavyycaredfrnrrrlwyvmdywgqgtlv
tvssastkgpsvfplapssgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2qqlL (L:)
diqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvps
rfsgsgsgtdftltisslqpedfatyycqqawaylptfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec