PDB entry 2qon

View 2qon on RCSB PDB site
Description: Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742A triple mutant
Class: transferase
Keywords: receptor tyrosine kinase, juxtamembrane segment, structural genomics, mutant, Structural Genomics Consortium, SGC, ATP-binding, Nucleotide-binding, Phosphorylation, Transferase, Transmembrane, Tyrosine-protein kinase
Deposited on 2007-07-20, released 2007-08-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ephrin receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHA3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6P4R6
      • engineered (21)
      • engineered (167)
    Domains in SCOPe 2.08: d2qona_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qonA (A:)
gsdekrlhfgnghlklpglrtfvdphtfedptqtvhefakeldatnisidkvvgagefge
vcsgrlklpskkeisvaiktlkvgytekqrrdflgeasimgqfdhpniirlegvvtkskp
vmivteymengsldsflrkhdaqftviqlvgmlrgiasgmkylsdmgavhrdlaarnili
nsnlvckvsdfglsrvleddpeaayttrggkipirwtspeaiayrkftsasdvwsygivl
wevmsygerpywemsnqdvikavdegyrlpppmdcpaalyqlmldcwqkdrnnrpkfeqi
vsildklirnpgslkiitsaaarpsnllldqsnvdittfrttgdwlngvwtahckeiftg
veysscdtiakis

    Sequence, based on observed residues (ATOM records): (download) 
    >2qonA (A:)
tfvtvhefakeldatnisidkvvgagefgevcsgrlklpskkeisvaiktlkvgytekqr
rdflgeasimgqfdhpniirlegvvtkskpvmivteymengsldsflrkhdaqftviqlv
gmlrgiasgmkylsdmgavhrdlaarnilinsnlvckvsdfglsripirwtspeaiayrk
ftsasdvwsygivlwevmsygerpywemsnqdvikavdegyrlpppmdcpaalyqlmldc
wqkdrnnrpkfeqivsildklirnpgslkiitsapsnllldq