PDB entry 2qkb

View 2qkb on RCSB PDB site
Description: Human RNase H catalytic domain mutant D210N in complex with 20-mer RNA/DNA hybrid
Class: hydrolase/DNA/RNA
Keywords: RNase H; RNA/DNA hybrid, HYDROLASE-DNA-RNA COMPLEX
Deposited on 2007-07-10, released 2007-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ribonuclease H1
    Species: Homo sapiens [TaxId:9606]
    Gene: RNASEH1, RNH1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60930 (3-153)
      • expression tag (0-2)
      • engineered (77)
    Domains in SCOPe 2.08: d2qkba1, d2qkba2
  • Chain 'B':
    Compound: Ribonuclease H1
    Species: Homo sapiens [TaxId:9606]
    Gene: RNASEH1, RNH1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60930 (3-153)
      • expression tag (0-2)
      • engineered (77)
    Domains in SCOPe 2.08: d2qkbb1, d2qkbb2
  • Chain 'C':
    Compound: 5'-r(*gp*gp*ap*gp*up*gp*cp*gp*ap*cp*ap*cp*cp*up*gp*ap*up*up*cp*c)-3')
  • Chain 'D':
    Compound: 5'-d(*dgp*dgp*dap*dap*dtp*dcp*dap*dgp*dgp*dtp*dgp*dtp*dcp*dgp*dcp*dap*dcp*dtp*dcp*dt)-3'
  • Heterogens: SO4, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qkbA (A:)
gshmgdfvvvytdgccssngrrrpragigvywgpghplnvgirlpgrqtnqraeihaack
aieqaktqninklvlytnsmftingitnwvqgwkkngwktsagkevinkedfvalerltq
gmdiqwmhvpghsgfigneeadrlaregakqsed

    Sequence, based on observed residues (ATOM records): (download) 
    >2qkbA (A:)
gshmgdfvvvytdgccssngrrrpragigvywgpghplnvgirlpgrqtnqraeihaack
aieqaktqninklvlytnsmftingitnwvqgwkkngwktsagkevinkedfvalerltq
gmdiqwmhvpghsgfigneeadrlaregakqs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qkbB (B:)
gshmgdfvvvytdgccssngrrrpragigvywgpghplnvgirlpgrqtnqraeihaack
aieqaktqninklvlytnsmftingitnwvqgwkkngwktsagkevinkedfvalerltq
gmdiqwmhvpghsgfigneeadrlaregakqsed

    Sequence, based on observed residues (ATOM records): (download) 
    >2qkbB (B:)
shmgdfvvvytdgccssnrrrpragigvywgpghplnvgirlpgrqtnqraeihaackai
eqaktqninklvlytnsmftingitnwvqgwkkngwktsagkevinkedfvalerltqgm
diqwmhvpghsgfigneeadrlaregakqs

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.