PDB entry 2qk9

View 2qk9 on RCSB PDB site
Description: Human RNase H catalytic domain mutant D210N in complex with 18-mer RNA/DNA hybrid
Class: hydrolase/DNA/RNA
Keywords: RNase H; RNA/DNA hybrid, HYDROLASE-DNA-RNA COMPLEX
Deposited on 2007-07-10, released 2007-11-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.19
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ribonuclease H1
    Species: Homo sapiens [TaxId:9606]
    Gene: RNASEH1, RNH1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60930 (3-153)
      • expression tag (1-2)
      • engineered (77)
    Domains in SCOPe 2.07: d2qk9a1, d2qk9a2
  • Chain 'B':
    Compound: 5'-r(*ap*gp*up*gp*cp*gp*ap*cp*ap*cp*cp*up*gp*ap*up*up*cp*c)-3'
  • Chain 'C':
    Compound: 5'-d(*gp*gp*ap*ap*tp*cp*ap*gp*gp*tp*gp*tp*cp*gp*cp*ap*cp*t)-3'
  • Heterogens: SO4, NA, FLC, 16D, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qk9A (A:)
gshmgdfvvvytdgccssngrrrpragigvywgpghplnvgirlpgrqtnqraeihaack
aieqaktqninklvlytnsmftingitnwvqgwkkngwktsagkevinkedfvalerltq
gmdiqwmhvpghsgfigneeadrlaregakqsed

    Sequence, based on observed residues (ATOM records): (download) 
    >2qk9A (A:)
shmgdfvvvytdgccssngrrrpragigvywgpghplnvgirlpgrqtnqraeihaacka
ieqaktqninklvlytnsmftingitnwvqgwkkngwktsagkevinkedfvalerltqg
mdiqwmhvpghsgfigneeadrlaregakqsed

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.