PDB entry 2qj4

View 2qj4 on RCSB PDB site
Description: A Mechanistic Basis for Converting a Receptor Tyrosine Kinase Agonist to an Antagonist
Class: hormone
Keywords: hgf/sf, hormone/growth factor
Deposited on 2007-07-06, released 2007-09-18
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.173
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hepatocyte growth factor
    Species: Mus musculus [TaxId:10090]
    Gene: Hgf
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2qj4a1, d2qj4a2
  • Chain 'B':
    Compound: hepatocyte growth factor
    Species: Mus musculus [TaxId:10090]
    Gene: Hgf
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2qj4b1, d2qj4b2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2qj4A (A:)
    gsyaegqkkrrntlhefkksakttltkedpllkiktkkvnsadecanrcirnrgftftck
    afvfdksrkrcywypfnsmssgvkkgfghefdlyenkdyirnciigkggsykgtvsitks
    gikcqpwnsmiphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipq
    csev
    

    Sequence, based on observed residues (ATOM records): (download)
    >2qj4A (A:)
    tlhefkksakttltkedpllkiktkkvnsadecanrcirnrgftftckafvfdksrkrcy
    wypfnsmssgvkkgfghefdlyenkdyirnciigkggsykgtvsitksgikcqpwnsmip
    hehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcsev
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2qj4B (B:)
    gsyaegqkkrrntlhefkksakttltkedpllkiktkkvnsadecanrcirnrgftftck
    afvfdksrkrcywypfnsmssgvkkgfghefdlyenkdyirnciigkggsykgtvsitks
    gikcqpwnsmiphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipq
    csev
    

    Sequence, based on observed residues (ATOM records): (download)
    >2qj4B (B:)
    tlhefkksakttltkedpllkiktkkvnsadecanrcirnrgftftckafvfdksrkrcy
    wypfnsmssgvkkgfghefdlyenkdyirnciigkggsykgtvsitksgikcqpwnsmip
    hehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcsev