PDB entry 2qfx

View 2qfx on RCSB PDB site
Description: Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADPH, a-ketoglutarate and Ca(2+)
Class: oxidoreductase
Keywords: Rossmann fold, Oxidoreductase
Deposited on 2007-06-28, released 2008-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfxa_
  • Chain 'B':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfxb_
  • Chain 'C':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfxc_
  • Chain 'D':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfxd_
  • Chain 'E':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfxe_
  • Chain 'F':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfxf_
  • Heterogens: CA, NDP, AKG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qfxA (A:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfxA (A:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qfxB (B:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfxB (B:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2qfxC (C:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfxC (C:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2qfxD (D:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfxD (D:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2qfxE (E:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfxE (E:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2qfxF (F:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfxF (F:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks