PDB entry 2qfv

View 2qfv on RCSB PDB site
Description: Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADP(+)
Class: Oxidoreductase
Keywords: Rossmann fold, Oxidoreductase
Deposited on 2007-06-28, released 2008-07-01
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.198
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2qfva_
  • Chain 'B':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2qfvb_
  • Chain 'C':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2qfvc_
  • Chain 'D':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2qfvd_
  • Heterogens: NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qfvA (A:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfvA (A:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qfvB (B:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfvB (B:)
kikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqdaae
aikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprlvp
rwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgvama
myntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskfeq
lgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpdgk
tfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfaniles
atlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2qfvC (C:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfvC (C:)
skikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqdaa
eaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprlv
prwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgvam
amyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskfe
qlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpdg
ktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanile
satlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeik

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2qfvD (D:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfvD (D:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks