PDB entry 2qfa

View 2qfa on RCSB PDB site
Description: Crystal structure of a Survivin-Borealin-INCENP core complex
Class: Cell cycle/Cell cycle/Cell cycle
Keywords: three-helical-bundle, long helix, protein complex, Alternative splicing, Apoptosis, Cell cycle, Cell division, Centromere, Chromosomal protein, Cytoplasm, Metal-binding, Mitosis, Nucleus, Phosphorylation, Polymorphism, Protease inhibitor, Thiol protease inhibitor, Zinc, Coiled coil, Microtubule, Cell cycle/Cell cycle/Cell cycle COMPLEX
Deposited on 2007-06-27, released 2007-11-06
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.186
AEROSPACI score: 0.71 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Baculoviral IAP repeat-containing protein 5
  Species: Homo sapiens [TaxId:9606]
  Gene: BIRC5, API4, IAP4
  Database cross-references and differences (RAF-indexed):
  • Uniprot O15392
  Domains in SCOPe 2.06: d2qfaa_
• Chain 'B':
  Compound: Borealin
  Species: Homo sapiens [TaxId:9606]
  Gene: CDCA8, PESCRG3
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q53HL2 (0-61)
• Chain 'C':
  Compound: Inner centromere protein
  Species: Homo sapiens [TaxId:9606]
  Gene: INCENP
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9NQS7 (Start-46)
• Heterogens: ZN, MES, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >2qfaA (A:)
  mgaptlppawqpflkdhristfknwpflegcactpermaeagfihcptenepdlaqcffc
  fkelegwepdddpieehkkhssgcaflsvkkqfeeltlgeflkldreraknkiaketnnk
  kkefeetakkvrraieqlaamd
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >2qfaA (A:)
  tlppawqpflkdhristfknwpflegcactpermaeagfihcptenepdlaqcffcfkel
  egwepdddpieehkkhssgcaflsvkkqfeeltlgeflkldreraknkiaketnnkkkef
  eetakkvrraieqlaam
  

  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  No sequence available.