PDB entry 2qel
View 2qel on RCSB PDB site
Description: Crystal structure of the highly amyloidogenic transthyretin mutant TTR G53S/E54D/L55S- heated protein
Class: transport protein
Keywords: Greek key, Beta barrel, Beta-slip, Protein heating, TRANSPORT PROTEIN
Deposited on
2007-06-26, released
2007-09-04
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-03-07, with a file datestamp of
2018-03-02.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: N/A
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2qela_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2qelb_ - Chain 'C':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2qelc_ - Chain 'D':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2qeld_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2qelA (A:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsessdshgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>2qelA (A:)
plmvkvldavrgspainvavhvfrkaaddtwepfasgktsessdshgltteeefvegiyk
veidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2qelB (B:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsessdshgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>2qelB (B:)
plmvkvldavrgspainvavhvfrkaaddtwepfasgktsessdshgltteeefvegiyk
veidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
- Chain 'C':
Sequence, based on SEQRES records: (download)
>2qelC (C:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsessdshgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>2qelC (C:)
lmvkvldavrgspainvavhvfrkaaddtwepfasgktsessdshgltteeefvegiykv
eidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'D':
Sequence, based on SEQRES records: (download)
>2qelD (D:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsessdshgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>2qelD (D:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsessdshgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp