PDB entry 2qe0

View 2qe0 on RCSB PDB site
Description: Thioacylenzyme Intermediate of GAPN from S. Mutans, New Data Integration and Refinement.
Class: oxidoreductase
Keywords: ALDH, GAPN, TERNARY COMPLEX, Oxidoreductase
Deposited on 2007-06-22, released 2007-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.19 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Gene: gapN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • variant (57)
      • variant (84)
      • engineered (249)
      • variant (346)
    Domains in SCOPe 2.08: d2qe0a_
  • Chain 'B':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Gene: gapN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • variant (57)
      • variant (84)
      • engineered (249)
      • variant (346)
    Domains in SCOPe 2.08: d2qe0b_
  • Chain 'C':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Gene: gapN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • variant (57)
      • variant (84)
      • engineered (249)
      • variant (346)
    Domains in SCOPe 2.08: d2qe0c_
  • Chain 'D':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Gene: gapN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • variant (57)
      • variant (84)
      • engineered (249)
      • variant (346)
    Domains in SCOPe 2.08: d2qe0d_
  • Heterogens: G3H, NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qe0A (A:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigk
magmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2qe0A (A:)
tkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsy
ieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmege
vleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptq
gsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigkm
agmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelv
ekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicp
ilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgia
eqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qe0B (B:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigk
magmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2qe0B (B:)
tkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsy
ieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmege
vleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptq
gsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigkm
agmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelv
ekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicp
ilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgia
eqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2qe0C (C:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigk
magmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2qe0C (C:)
tkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsy
ieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmege
vleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptq
gsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigkm
agmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelv
ekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicp
ilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgia
eqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2qe0D (D:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigk
magmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2qe0D (D:)
tkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsy
ieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmege
vleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptq
gsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigkm
agmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelv
ekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicp
ilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgia
eqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik