PDB entry 2qdp

View 2qdp on RCSB PDB site
Description: Crystal structure of the HePTP catalytic domain C270S mutant crystallized in ammonium acetate
Class: hydrolase
Keywords: HePTP, HUMAN HEMATOPOIETIC TYROSINE PHOSPHATASE CATALYTIC DOMAIN MUTANT, LC-PTP, PTPN7, HYDROLASE
Deposited on 2007-06-21, released 2008-06-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.72 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 7
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35236 (13-End)
      • engineered (239)
    Domains in SCOPe 2.08: d2qdpa_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qdpA (A:)
mgsdkihhhhhhmntprevtlhflrtaghpltrwalqrqppspkqleeeflkipsnfvsp
edldipghaskdryktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgp
mpntvsdfwemvwqeevslivmltqlregkekcvhywpteeetygpfqiriqdmkecpey
tvrqltiqyqeerrsvkhilfsawpdhqtpesagpllrlvaeveespetaahpgpivvhs
sagigrtgcfiatrigcqqlkargevdilgivcqlrldrggmiqtaeqyqflhhtlalya
gqlpeepsp

    Sequence, based on observed residues (ATOM records): (download) 
    >2qdpA (A:)
ntprevtlhflrtaghpltrwalqrqppspkqleeeflkipsnfvspedldipghaskdr
yktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgpmpntvsdfwemvw
qeevslivmltqlregkekcvhywpteeetygpfqiriqdmkecpeytvrqltiqyqeer
rsvkhilfsawpdhqtpesagpllrlvaeveespetaahpgpivvhssagigrtgcfiat
rigcqqlkargevdilgivcqlrldrggmiqtaeqyqflhhtlalyagqlpe