PDB entry 2qaf

View 2qaf on RCSB PDB site
Description: Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-iodo-UMP
Class: lyase
Keywords: Crystal structure,Plasmodium falciparum, orotidine 5'-phosphate decarboxylase,covalently,6-iodo-UMP, LYASE
Deposited on 2007-06-15, released 2008-04-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.175
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Orotidine 5' monophosphate decarboxylase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: ompdc
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8T6J6 (19-End)
      • expression tag (12-18)
    Domains in SCOPe 2.07: d2qafa2, d2qafa3
  • Chain 'B':
    Compound: Orotidine 5' monophosphate decarboxylase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: ompdc
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8T6J6 (19-End)
      • expression tag (18)
    Domains in SCOPe 2.07: d2qafb2, d2qafb3
  • Heterogens: SO4, U5P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qafA (A:)
mgsshhhhhhssglvprgsmgfkvklekrrnaintclcigldpdekdienfmknekenny
nnikknlkekyinnvsikkdillkapdniireekseeffyffnhfcfyiinetnkyaltf
kmnfafyipygsvgidvlknvfdylyelniptildmkindigntvknyrkfifeylksds
ctvniymgtnmlkdicydeeknkyysafvlvkttnpdsaifqknlsldnkqayvimaqea
lnmssylnleqnnefigfvvgansydemnyirtyfpncyilspgigaqngdlhktltngy
hksyekilinigraitknpypqkaaqmyydqinailkqnmes

    Sequence, based on observed residues (ATOM records): (download) 
    >2qafA (A:)
glvprgsmgfkvklekrrnaintclcigldpdekdienfmknekennynnikknlkekyi
nnvsikkdillkapdniireekseeffyffnhfcfyiinetnkyaltfkmnfafyipygs
vgidvlknvfdylyelniptildmkindigntvknyrkfifeylksdsctvniymgtnml
kdicydeeknkyysafvlvkttnpdsaifqknlsldnkqayvimaqealnmssylnleqn
nefigfvvgansydemnyirtyfpncyilspgigaqngdlhktltngyhksyekilinig
raitknpypqkaaqmyydqinailkqnme

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qafB (B:)
mgsshhhhhhssglvprgsmgfkvklekrrnaintclcigldpdekdienfmknekenny
nnikknlkekyinnvsikkdillkapdniireekseeffyffnhfcfyiinetnkyaltf
kmnfafyipygsvgidvlknvfdylyelniptildmkindigntvknyrkfifeylksds
ctvniymgtnmlkdicydeeknkyysafvlvkttnpdsaifqknlsldnkqayvimaqea
lnmssylnleqnnefigfvvgansydemnyirtyfpncyilspgigaqngdlhktltngy
hksyekilinigraitknpypqkaaqmyydqinailkqnmes

    Sequence, based on observed residues (ATOM records): (download) 
    >2qafB (B:)
smgfkvklekrrnaintclcigldpdekdienfmknekennynnikknlkekyinnvsik
kdillkapdniireekseeffyffnhfcfyiinetnkyaltfkmnfafyipygsvgidvl
knvfdylyelniptildmkindigntvknyrkfifeylksdsctvniymgtnmlkdicyd
eeknkyysafvlvkttnpdsaifqknlsldnkqayvimaqealnmssylnleqnnefigf
vvgansydemnyirtyfpncyilspgigaqngdlhktltngyhksyekilinigraitkn
pypqkaaqmyydqinailkqnm