PDB entry 2q8m

View 2q8m on RCSB PDB site
Description: T-like Fructose-1,6-bisphosphatase from Escherichia coli with AMP, Glucose 6-phosphate, and Fructose 1,6-bisphosphate bound
Class: Hydrolase
Keywords: GLYCOLYSIS, GLUCONEOGENESIS, BACTERIA, CARBOHYDRATE METABOLISM, DIABETES, PROTEIN-PROTEIN INTERACTIONS, PROTEOBACTERIA, GRAM-NEGATIVE, PROTEIN CRYSTALLOGRAPHY, HETEROTROPHIC, ALLOSTERIC REGULATION, Hydrolase
Deposited on 2007-06-11, released 2007-06-19
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.209
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fructose-bisphosphatase
    Species: Shigella boydii [TaxId:621]
    Gene: fbp
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q31TG8 (0-331)
      • modified residue (0)
      • modified residue (108)
      • modified residue (165)
      • modified residue (193)
      • modified residue (278)
      • modified residue (317)
    Domains in SCOPe 2.03: d2q8ma_
  • Chain 'B':
    Compound: Fructose-bisphosphatase
    Species: Shigella boydii [TaxId:621]
    Gene: fbp
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q31TG8 (0-331)
      • modified residue (0)
      • modified residue (108)
      • modified residue (165)
      • modified residue (193)
      • modified residue (278)
      • modified residue (317)
    Domains in SCOPe 2.03: d2q8mb_
  • Heterogens: BG6, FBP, MG, CL, AMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2q8mA (A:)
mktlgefivekqhefshatgeltallsaiklgakiihrdinkaglvdilgasgaenvqge
vqqkldlfaneklkaalkardivagiaseeedeivvfegcehakyvvlmdpldgssnidv
nvsvgtifsiyrrvtpvgtpvteedflqpgnkqvaagyvvygsstmlvyttgcgvhafty
dpslgvfclcqermrfpekgktysinegnyikfpngvkkyikfcqeedkstnrpytsryi
gslvadfhrnllkggiylypstashpdgklrllyecnpmaflaeqaggkasdgkerildi
ipetlhqrrsffvgndhmvedverfirefpda

    Sequence, based on observed residues (ATOM records): (download) 
    >2q8mA (A:)
mktlgefivekqhefshatgeltallsaiklgakiihrdinkaglfaneklkaalkardi
vagiaseeedeivvfegcehakyvvlmdpldgssnidvnvsvgtifsiyrrvtpvgtpvt
eedflqpgnkqvaagyvvygsstmlvyttgcgvhaftydpslgvfclcqermrfpekgkt
ysinegnyikfpngvkkyikfcqeedkstnrpytsryigslvadfhrnllkggiylypst
ashpdgklrllyecnpmaflaeqaggkasdgkerildiipetlhqrrsffvgndhmvedv
erfirefpda

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2q8mB (B:)
mktlgefivekqhefshatgeltallsaiklgakiihrdinkaglvdilgasgaenvqge
vqqkldlfaneklkaalkardivagiaseeedeivvfegcehakyvvlmdpldgssnidv
nvsvgtifsiyrrvtpvgtpvteedflqpgnkqvaagyvvygsstmlvyttgcgvhafty
dpslgvfclcqermrfpekgktysinegnyikfpngvkkyikfcqeedkstnrpytsryi
gslvadfhrnllkggiylypstashpdgklrllyecnpmaflaeqaggkasdgkerildi
ipetlhqrrsffvgndhmvedverfirefpda

    Sequence, based on observed residues (ATOM records): (download) 
    >2q8mB (B:)
mktlgefivekqhefshatgeltallsaiklgakiihrdinkaglfaneklkaalkardi
vagiaseeedeivvfegcehakyvvlmdpldgssnidvnvsvgtifsiyrrvtpvgtpvt
eedflqpgnkqvaagyvvygsstmlvyttgcgvhaftydpslgvfclcqermrfpekgkt
ysinegnyikfpngvkkyikfcqeedkstnrpytsryigslvadfhrnllkggiylypst
ashpdgklrllyecnpmaflaeqaggkasdgkerildiipetlhqrrsffvgndhmvedv
erfirefpda