PDB entry 2q7n

View 2q7n on RCSB PDB site
Description: Crystal structure of Leukemia inhibitory factor in complex with LIF receptor (domains 1-5)
Class: CYTOKINE receptor/CYTOKINE
Keywords: CYTOKINE CELL SURFACE RECEPTOR COMPLEX LIFR LIF, CYTOKINE receptor-CYTOKINE COMPLEX
Deposited on 2007-06-07, released 2007-07-31
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 4 Å
R-factor: 0.24
AEROSPACI score: 0.05 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukemia inhibitory factor receptor
    Species: Mus musculus [TaxId:10090]
    Gene: Lifr
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: leukemia inhibitory factor
    Species: Homo sapiens [TaxId:9606]
    Gene: LIF, HILDA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2q7nb1
  • Chain 'C':
    Compound: Leukemia inhibitory factor receptor
    Species: Mus musculus [TaxId:10090]
    Gene: Lifr
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: leukemia inhibitory factor
    Species: Homo sapiens [TaxId:9606]
    Gene: LIF, HILDA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2q7nd1
  • Heterogens: NAG

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2q7nB (B:)
splpitpvnatcairhpchnnlmnqirsqlaqlngsanalfilyytaqgepfpnnldklc
gpnvtdfppfhangtekaklvelyrivvylgtslgnitrdqkilnpsalslhsklnatad
ilrgllsnvlcrlcskyhvghvdvtygpdtsgkdvfqkkklgcqllgkykqiiavlaqaf

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2q7nD (D:)
splpitpvnatcairhpchnnlmnqirsqlaqlngsanalfilyytaqgepfpnnldklc
gpnvtdfppfhangtekaklvelyrivvylgtslgnitrdqkilnpsalslhsklnatad
ilrgllsnvlcrlcskyhvghvdvtygpdtsgkdvfqkkklgcqllgkykqiiavlaqaf