PDB entry 2q72

View 2q72 on RCSB PDB site
Description: Crystal Structure Analysis of LeuT complexed with L-leucine, sodium, and imipramine
Class: transport protein
Keywords: membrane protein, neurotransmitter sodium symporter, occluded, tricyclic antidepressant, TRANSPORT PROTEIN
Deposited on 2007-06-05, released 2007-08-21
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.203
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transporter
    Species: Aquifex aeolicus [TaxId:224324]
    Gene: snf
    Database cross-references and differences (RAF-indexed):
    • Uniprot O67854 (Start-512)
      • cloning artifact (513-515)
    Domains in SCOPe 2.05: d2q72a_
  • Heterogens: BOG, NA, LEU, IXX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2q72A (A:)
mevkrehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmw
iewamgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfai
kflvglvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinv
silirgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkd
pgvwiaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisip
aavaffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaim
qpmiafledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffgltel
iiffwifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeeth
wtvwitrfyiiglflfltflvflaerrrnhesagtlvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >2q72A (A:)
krehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiew
amgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikfl
vglvpeppptdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilir
giskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwi
aavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaf
fgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmia
fledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffw
ifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwi
trfyiiglflfltflvflaerrrnhesagtl