PDB entry 2q6n

View 2q6n on RCSB PDB site
Description: Structure of Cytochrome P450 2B4 with Bound 1-(4-cholorophenyl)imidazole
Class: oxidoreductase
Keywords: p450, Monooxygenase, Oxidoreductase, membrane protein, CYP 2B4, CYP LM2
Deposited on 2007-06-05, released 2007-11-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.233
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (Start-471)
      • engineered (9)
      • engineered (201)
      • engineered (206)
      • expression tag (472)
    Domains in SCOPe 2.08: d2q6na1, d2q6na2
  • Chain 'B':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (Start-471)
      • engineered (9)
      • engineered (201)
      • engineered (206)
      • expression tag (472)
    Domains in SCOPe 2.08: d2q6nb1, d2q6nb2
  • Chain 'C':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (Start-471)
      • engineered (9)
      • engineered (201)
      • engineered (206)
      • expression tag (472)
    Domains in SCOPe 2.08: d2q6nc1, d2q6nc2
  • Chain 'D':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (Start-471)
      • engineered (9)
      • engineered (201)
      • engineered (206)
      • expression tag (472)
    Domains in SCOPe 2.08: d2q6nd1, d2q6nd2
  • Chain 'E':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (Start-471)
      • engineered (9)
      • engineered (201)
      • engineered (206)
      • expression tag (472)
    Domains in SCOPe 2.08: d2q6ne1, d2q6ne2
  • Chain 'F':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (Start-471)
      • engineered (9)
      • engineered (201)
      • engineered (206)
      • expression tag (472)
    Domains in SCOPe 2.08: d2q6nf1, d2q6nf2
  • Chain 'G':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (Start-471)
      • engineered (9)
      • engineered (201)
      • engineered (206)
      • expression tag (472)
    Domains in SCOPe 2.08: d2q6ng1, d2q6ng2
  • Heterogens: HEM, 1CI

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2q6nA (A:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2q6nA (A:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgkrsveeriq
eearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfs
lissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidv
yllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqke
ieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipknte
vfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelf
lffttilqnfsiaspvppedidltpresgvgnvppsyqirflarh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2q6nB (B:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2q6nB (B:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgkrsveeriq
eearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfs
lissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidv
yllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqke
ieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipknte
vfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelf
lffttilqnfsiaspvppedidltpresgvgnvppsyqirflarh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2q6nC (C:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2q6nC (C:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgkrsveeriq
eearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfs
lissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidv
yllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqke
ieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipknte
vfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelf
lffttilqnfsiaspvppedidltpresgvgnvppsyqirflarh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2q6nD (D:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2q6nD (D:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgkrsveeriq
eearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfs
lissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidv
yllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqke
ieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipknte
vfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelf
lffttilqnfsiaspvppedidltpresgvgnvppsyqirflarh

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2q6nE (E:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2q6nE (E:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgkrsveeriq
eearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfs
lissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidv
yllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqke
ieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipknte
vfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelf
lffttilqnfsiaspvppedidltpresgvgnvppsyqirflarh

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2q6nF (F:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2q6nF (F:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgkrsveeriq
eearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfs
lissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidv
yllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqke
ieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipknte
vfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelf
lffttilqnfsiaspvppedidltpresgvgnvppsyqirflarh

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2q6nG (G:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2q6nG (G:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgkrsveeriq
eearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfs
lissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidv
yllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqke
ieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipknte
vfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelf
lffttilqnfsiaspvppedidltpresgvgnvppsyqirflarh