SCOPe 2.08: Structural Classification of Proteins

PDB entry 2q5d

View 2q5d on RCSB PDB site
Description: Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form
Class: protein transport
Keywords: heat repeat, ibb-domain, importin, karyopherin, snurportin, protein transport
Deposited on 2007-05-31, released 2008-01-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-04-02, with a file datestamp of 2014-03-28.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.303
AEROSPACI score: 0.05 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: importin beta-1 subunit
Species: Homo sapiens [TaxId:9606]
Gene: KPNB1, NTF97
Database cross-references and differences (RAF-indexed):
- Uniprot Q14974 (0-875)
Domains in SCOPe 2.08: d2q5da_
Chain 'B':
Compound: importin beta-1 subunit
Species: Homo sapiens [TaxId:9606]
Gene: KPNB1, NTF97
Database cross-references and differences (RAF-indexed):
- Uniprot Q14974 (0-875)
Domains in SCOPe 2.08: d2q5db_
Chain 'C':
Compound: Snurportin-1
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot O95149 (Start-39)
Domains in SCOPe 2.08: d2q5dc_
Chain 'D':
Compound: Snurportin-1
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot O95149 (Start-39)
Domains in SCOPe 2.08: d2q5dd_

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2q5dA (A:)
melitilektvspdrleleaaqkfleraavenlptflvelsrvlanpgnsqvarvaaglq
iknsltskdpdikaqyqqrwlaidanarrevknyvlqtlgtetyrpssasqcvagiacae
ipvnqwpelipqlvanvtnpnstehmkestleaigyicqdidpeqlqdksneiltaiiqg
mrkeepsnnvklaatnallnsleftkanfdkeserhfimqvvceatqcpdtrvrvaalqn
lvkimslyyqymetymgpalfaitieamksdidevalqgiefwsnvcdeemdlaieasea
aeqgrppehtskfyakgalqylvpiltqtltkqdendddddwnpckaagvclmllatcce
ddivphvlpfikehiknpdwryrdaavmafgcilegpepsqlkplviqamptlielmkdp
svvvrdtaawtvgricellpeaaindvylapllqclieglsaeprvasnvcwafsslaea
ayeaadvaddqeepatyclsssfelivqkllettdrpdghqnnlrssayeslmeivknsa
kdcypavqkttlvimerlqqvlqmeshiqstsdriqfndlqsllcatlqnvlrkvqhqda
lqisdvvmasllrmfqstagsggvqedalmavstlvevlggeflkymeafkpflgiglkn
yaeyqvclaavglvgdlcralqsniipfcdevmqlllenlgnenvhrsvkpqilsvfgdi
alaiggefkkylevvlntlqqasqaqvdksdydmvdylnelrescleaytgivqglkgdq
envhpdvmlvqprvefilsfidhiagdedhtdgvvacaagligdlctafgkdvlklvear
pmihelltegrrsktnkaktlatwatkelrklknqa

Sequence, based on observed residues (ATOM records): (download)

>2q5dA (A:)
melitilektvspdrleleaaqkfleraavenlptflvelsrvlanpgnsqvarvaaglq
iknsltskdpdikaqyqqrwlaidanarrevknyvlqtlgtetyrpssasqcvagiacae
ipvnqwpelipqlvanvtnpnstehmkestleaigyicqdidpeqlqdksneiltaiiqg
mrkeepsnnvklaatnallnsleftkanfdkeserhfimqvvceatqcpdtrvrvaalqn
lvkimslyyqymetymgpalfaitieamksdidevalqgiefwsnvcdeemdlaieasea
aeqgrppehtskfyakgalqylvpiltqtltkqdendddddwnpckaagvclmllatcce
ddivphvlpfikehiknpdwryrdaavmafgcilegpepsqlkplviqamptlielmkdp
svvvrdtaawtvgricellpeaaindvylapllqclieglsaeprvasnvcwafsslaea
ayeaadvaddqeepatyclsssfelivqkllettdrpdghqnnlrssayeslmeivknsa
kdcypavqkttlvimerlqqvlqmeshiqstsdriqfndlqsllcatlqnvlrkvqhqda
lqisdvvmasllrmfqstagsggvqedalmavstlvevlggeflkymeafkpflgiglkn
yaeyqvclaavglvgdlcralqsniipfcdevmqlllenlgnenvhrsvkpqilsvfgdi
alaiggefkkylevvlntlqqasqaqvdmvdylnelrescleaytgivqglkgdqenvhp
dvmlvqprvefilsfidhiagdedhtdgvvacaagligdlctafgkdvlklvearpmihe
lltegrrsktnkaktlatwatkelrklknqa

Chain 'B':
Sequence, based on SEQRES records: (download)

>2q5dB (B:)
melitilektvspdrleleaaqkfleraavenlptflvelsrvlanpgnsqvarvaaglq
iknsltskdpdikaqyqqrwlaidanarrevknyvlqtlgtetyrpssasqcvagiacae
ipvnqwpelipqlvanvtnpnstehmkestleaigyicqdidpeqlqdksneiltaiiqg
mrkeepsnnvklaatnallnsleftkanfdkeserhfimqvvceatqcpdtrvrvaalqn
lvkimslyyqymetymgpalfaitieamksdidevalqgiefwsnvcdeemdlaieasea
aeqgrppehtskfyakgalqylvpiltqtltkqdendddddwnpckaagvclmllatcce
ddivphvlpfikehiknpdwryrdaavmafgcilegpepsqlkplviqamptlielmkdp
svvvrdtaawtvgricellpeaaindvylapllqclieglsaeprvasnvcwafsslaea
ayeaadvaddqeepatyclsssfelivqkllettdrpdghqnnlrssayeslmeivknsa
kdcypavqkttlvimerlqqvlqmeshiqstsdriqfndlqsllcatlqnvlrkvqhqda
lqisdvvmasllrmfqstagsggvqedalmavstlvevlggeflkymeafkpflgiglkn
yaeyqvclaavglvgdlcralqsniipfcdevmqlllenlgnenvhrsvkpqilsvfgdi
alaiggefkkylevvlntlqqasqaqvdksdydmvdylnelrescleaytgivqglkgdq
envhpdvmlvqprvefilsfidhiagdedhtdgvvacaagligdlctafgkdvlklvear
pmihelltegrrsktnkaktlatwatkelrklknqa

Sequence, based on observed residues (ATOM records): (download)

>2q5dB (B:)
melitilektvspdrleleaaqkfleraavenlptflvelsrvlanpgnsqvarvaaglq
iknsltskdpdikaqyqqrwlaidanarrevknyvlqtlgtetyrpssasqcvagiacae
ipvnqwpelipqlvanvtnpnstehmkestleaigyicqdidpeqlqdksneiltaiiqg
mrkeepsnnvklaatnallnsleftkanfdkeserhfimqvvceatqcpdtrvrvaalqn
lvkimslyyqymetymgpalfaitieamksdidevalqgiefwsnvcdeemdlaieasea
aeqgrppehtskfyakgalqylvpiltqtltkqdendddddwnpckaagvclmllatcce
ddivphvlpfikehiknpdwryrdaavmafgcilegpepsqlkplviqamptlielmkdp
svvvrdtaawtvgricellpeaaindvylapllqclieglsaeprvasnvcwafsslaea
ayeaadvaddqeepatyclsssfelivqkllettdrpdghqnnlrssayeslmeivknsa
kdcypavqkttlvimerlqqvlqmsdriqfndlqsllcatlqnvlrkvqhqdalqisdvv
masllrmfqstagsggvqedalmavstlvevlggeflkymeafkpflgigqvclaavglv
gdlcralqsniipfcdevmqlllenlgnenvhrsvkpqilsvfgdialaiggefkkylev
vlntlqqasqaqvylnelrescleaytgivqgqpdvmlvqprvefilsfidhiagdedht
dgvvacaagligdlctafgkdvlklvearpmihelltegrrsktnkaktlatwatkelrk
lknqa

Chain 'C':
Sequence, based on SEQRES records: (download)
```
>2q5dC (C:)
hprlsqykskyssleqserrrrllelqkskrldyvnharr
```
Sequence, based on observed residues (ATOM records): (download)
```
>2q5dC (C:)
prlsqykskyeqserrrrllelqkskrldyvnharr
```
Chain 'D':
Sequence, based on SEQRES records: (download)
```
>2q5dD (D:)
hprlsqykskyssleqserrrrllelqkskrldyvnharr
```
Sequence, based on observed residues (ATOM records): (download)
```
>2q5dD (D:)
errrrllelqkskrldyvnharr
```