PDB entry 2q4r

View 2q4r on RCSB PDB site
Description: Ensemble refinement of the protein crystal structure of human phosphomannomutase 2 (PMM2)
Class: isomerase
Keywords: Ensemble Refinement, Refinement Methodology Development, HS.459855, HS.313504, BC008310, PHOSPHATASE, PFAM PF03332, HAD SUPERFAMILY, JAECKEN DISEASE, CARBOHYDRATE-DEFICIENT GLYCOPROTEIN SYNDROME, Structural Genomics, Protein Structure Initiative, PSI, Center for Eukaryotic Structural Genomics, CESG, ISOMERASE
Deposited on 2007-05-31, released 2007-06-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-08-10, with a file datestamp of 2011-08-05.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: 0.207
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphomannomutase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PMM2, HS.459855
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15305 (Start-245)
      • modified residue (27)
      • modified residue (125)
      • modified residue (211)
      • modified residue (226)
    Domains in SCOPe 2.07: d2q4ra_
  • Heterogens: EDO, GLY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2q4rA (A:)
saapgpalclfdvdgtltaprqkitkemddflqklrqkikigvvggsdfekvqeqlgndv
vekydyvfpenglvaykdgkllcrqniqshlgealiqdlinyclsyiakiklpkkrgtfi
efrngmlnvspigrscsqeeriefyeldkkenirqkfvadlrkefagkgltfsiggqisf
dvfpdgwdkryclrhvendgyktiyffgdktmpggndheiftdprtmgysvtapedtrri
cellfs

    Sequence, based on observed residues (ATOM records): (download) 
    >2q4rA (A:)
pgpalclfdvdgtltaprqkitkemddflqklrqkikigvvggsdfekvqeqlgndvvek
ydyvfpenglvaykdgkllcrqniqshlgealiqdlinyclsyiakiklpkkrgtfiefr
ngmlnvspigrscsqeeriefyeldkkenirqkfvadlrkefagkgltfsiggqisfdvf
pdgwdkryclrhvendgyktiyffgdktmndheiftdprtmgysvtapedtrricellfs