PDB entry 2q1j
View 2q1j on RCSB PDB site
Description: The discovery of glycine and related amino acid-based factor xa inhibitors
Class: hydrolase
Keywords: COAGULATION FXA, Blood coagulation, Calcium, Cleavage on pair of basic residues, EGF-like domain, Gamma-carboxyglutamic acid, Glycoprotein, Hydrolase, Hydroxylation, Polymorphism, Protease, Serine protease, Zymogen
Deposited on
2007-05-24, released
2007-08-14
The last revision prior to the SCOPe 2.07 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.23
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Activated factor Xa heavy chain (EC 3.4.21.6)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d2q1ja_ - Chain 'B':
Compound: Factor X light chain (EC 3.4.21.6)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d2q1jb_ - Heterogens: CA, FXI, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2q1jA (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2q1jB (B:)
lcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle